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Expression profiling in ovarian cancer reveals coordinated regulation of BRCA1/...

Custódio, Noélia; Savisaar, Rosina; Carvalho, Célia; Bak-Gordon, Pedro; Ribeiro, Maria I.; Almeida-Tavares, Joana; Nunes, Paula B.; Peixoto, Carolina

Predictive biomarkers are crucial in clarifying the best strategy to use poly(ADP-ribose) polymerase inhibitors (PARPi) for the greatest benefit to ovarian cancer patients. PARPi are specifically lethal to cancer cells that cannot repair DNA damage by homologous recombination (HR), and HR deficiency is frequently associated with BRCA1/2 mutations. Genetic tests for BRCA1/2 mutations are currently used in the cl...

Date: 2022   |   Origin: Repositório da Universidade de Lisboa
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Competências de liderança adquiridas no secundário pelos alunos do 1.º ano do e...

Bento, António V.; Ribeiro, Maria I.

Date: 2012   |   Origin: DigitUMa - Repositório da Universidade da Madeira
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