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New metallophamaceutic reduced renal injury induced by non-steroidal anti-infla...
Macêdo,Clóvis Ney Pinheiro; Braga,Francisco Evanilso Silva; Campelo,Ana Paula Bomfim Soares; Diniz,Gabriel Maia; Lopes,Luiz Gonzaga de FrançaAbstract Purpose To evaluate the effect of Rut-bpy (Cis-[Ru(bpy)2(SO3)(NO)]PF 6), a novel nitric oxide donor, able to modulate the histological changes caused by the NASID (meloxicam). Methods Wistar rats were assigned into three groups (n=6 rats/group): Sham group (saline solution), NSAID group (meloxicam - 15 mg/kg) and Rut-bpy group (100 mg/kg of Rut-bpy associated with 15mg/kg of meloxicam). At the end of e...
Date: 2019
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Origin: Oasisbr