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Concepts for the development of person-centred, digitally-enabled, Artificial I...

Bousquet, J; Schünemann, HJ; Sousa-Pinto, B; Zuberbier, T; Togias, A; Samolinski, B; Bedbrook, A; Czarlewski, W; Hofmann-Apitius, M; Litynska, J

The traditional healthcare model is focused on diseases (medicine and natural science) and does not acknowledge patients' resources and abilities to be experts in their own life based on their lived experiences. Improving healthcare safety, quality and coordination, as well as quality of life, are important aims in the care of patients with chronic conditions. Person-centred care needs to ensure that people's v...


Consistent Trajectories of Rhinitis Control and Treatment in 16,177 Weeks: The ...

Sousa‐Pinto, B; Schünemann, HJ; Sá‐Sousa, A; Vieira, RJ; Amaral, R; Anto, JM; Klimek, L; Czarlewski, W; Mullol, J; Pfaar, O; Bedbrook, A; Brussino, L

Introduction: Data from mHealth apps can provide valuable information on rhinitis control and treatment patterns. However, in MASK-air®, these data have only been analyzed cross-sectionally, without considering the changes of symptoms over time. We analyzed data from MASK-air® longitudinally, clustering weeks according to reported rhinitis symptoms. Methods: We analyzed MASK-air® data, assessing the weeks for w...


Rhinitis Associated with Asthma is Distinct from Rhinitis Alone: The ARIA‐MeDAL...

Bousquet, J; Melén, E; Haahtela, T; Koppelman, GH; Togias, A; Valenta, R; Akdis, CA; Czarlewski, W; Rothenberg, M; Valiulis, A; Wickman, M; Akdis, M

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of "one-airway-one-disease," coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhiniti...


Digitally‐Enabled, Patient‐Centred Care in Rhinitis and Asthma Multimorbidity: ...

Bousquet, J; Anto, JM; Sousa‐Pinto, B; Czarlewski, W; Bedbrook, A; Haahtela, T; Klimek, L; Pfaar, O; Kuna, P; Kupczyk, M; Regateiro, FS; Samolinski, B

MASK-air® , a validated mHealth app (Medical Device regulation Class IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhinitis and asthma care. MASK-air® is a Good Practice of DG Santé on digitally-enabled, patient-centred care. It is also a candidate Good Practice of OECD (Organisation for Econo...


Comparison of Rhinitis Treatments Using MASK-air ® Data and Considering the Min...

Sousa‐Pinto, B; Schünemann, HJ; Sá‐Sousa, A; Vieira, RJ; Amaral, R; Anto, JM; Klimek, L; Czarlewski, W; Mullol, J; Pfaar, O; Bedbrook, A; Brussino, L

Background: Different treatments exist for allergic rhinitis (AR), including pharmacotherapy and allergen immunotherapy (AIT), but they have not been compared using direct patient data (i.e., "real-world data"). We aimed to compare AR pharmacological treatments on (i) daily symptoms, (ii) frequency of use in co-medication, (iii) visual analogue scales (VASs) on allergy symptom control considering the minimal im...


Allergen Immunotherapy in MASK‐Air Users in Real‐Life: Results of a Bayesian Mi...

Sousa‐Pinto, B; Azevedo, LF; Sá‐Sousa, A; Vieira, RJ; Amaral, R; Klimek, L; Czarlewski, W; Anto, JM; Bedbrook, A; Kvedariene, V; Ventura, MT

Background: Evidence regarding the effectiveness of allergen immunotherapy (AIT) on allergic rhinitis has been provided mostly by randomised controlled trials, with little data from real-life studies. Objective: To compare the reported control of allergic rhinitis symptoms in three groups of users of the MASK-air® app: those receiving sublingual AIT (SLIT), those receiving subcutaneous AIT (SCIT), and those rec...


ARIA Digital Anamorphosis: Digital Transformation of Health and Care in Airway ...

Bousquet, J; Anto, JM; Bachert, C; Haahtela, T; Zuberbier, T; Czarlewski, W; Bedbrook, A; Bosnic-Anticevich, S; Walter Canonica, G; Cardona, V; Costa, E

Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validate...


Treatment of Allergic Rhinitis Using Mobile Technology with Real-World Data: th...

Bousquet, J; Devillier, P; Arnavielhe, S; Bedbrook, A; Alexis-Alexandre, G; van Eerd, M; Murray, R; Canonica, GW; Illario, M; Menditto, E

Background: Large observational implementation studies are needed to triangulate the findings from randomized control trials as they reflect "real-world" everyday practice. In a pilot study, we attempted to provide additional and complementary insights on the real-life treatment of allergic rhinitis (AR) using mobile technology. Methods: A mobile phone app (Allergy Diary, freely available in Google Play and App...


ARIA 2016: Care pathways implementing emerging technologies for predictive medi...

Bousquet, J; Hellings, PW; Agache, I; Bedbrook, A; Bachert, C; Bergmann, KC; Bewick, M; Bindslev-Jensen, C; Bosnic-Anticevitch, S; Bucca, C; Caimmi, DP

The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a World Health Organization workshop in 1999. The initial goals were (1) to propose a new allergic rhinitis classification, (2) to promote the concept of multi-morbidity in asthma and rhinitis and (3) to develop guidelines with all stakeholders that could be used globally for all countries and populations. ARIA-disseminated and im...


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