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Global hippocampal atrophy in major depressive disorder: a meta-analysis of mag...

Santos,Marcelo Antônio Oliveira; Bezerra,Lucas Soares; Carvalho,Ana Rita Marinho Ribeiro; Brainer-Lima,Alessandra Mertens

Abstract Introduction: Major depressive disorder (MDD), an incapacitating mental disorder, is characterized by episodes of at least 2 weeks of apparent changes in mood, cognition, and neurovegetative functions. Many neuroimaging studies using magnetic resonance imaging (MRI) have examined morphometric changes in patients with MDD, but the results are not conclusive. This study aims to review the literature and ...

Date: 2018   |   Origin: Oasisbr

Discordant clinical outcomes of congenital Zika virus infection in twin pregnan...

Linden,Vanessa van der; Linden Junior,Hélio van der; Leal,Mariana de Carvalho; Rolim Filho,Epitacio Leite; Linden,Ana van der

ABSTRACT Congenital Zika syndrome is an emergent cause of a congenital infectious disorder, resulting in severe damage to the central nervous system and microcephaly. Despite advances in understanding the pathophysiology of the disease, we still do not know all the mechanisms enrolled in the vertical transmission of the virus. As has already been reported in other types of congenital infectious disorders in diz...

Date: 2017   |   Origin: Oasisbr

Craniovertebral junction malformation in Northeastern Brazil: the myth of the D...

Vidal,Claudio Henrique Fernandes; Silva,Joacil Carlos da; Lins,Cicero Jose Pacheco; Brainer-Lima,Alessandra Mertens; Valenca,Marcelo Moraes

The high prevalence of craniovertebral junction malformation in Northeastern Brazil is historically associated with brachycephalic biotype (flat head), also common in this region. It has been postulated that this trait was introduced to this region by the Dutch during the colonial period in Brazil's history. Based on the confrontation of this paradigm against some historical facts, the authors concluded that th...

Date: 2013   |   Origin: Oasisbr

Extensive spinal cord involvement in magnetic resonance imaging evaluation on s...

Vidal,Claudio Henrique Fernandes; Ferreira,Maria Lucia Brito; Azevedo Filho,Hildo Rocha Cirne de; Gurgel,Fernando Viana; Brainer-Lima,Alessandra Mertens

The diagnosis of schistosomal myelitis (SM) is frequently presumptive because no findings from any complementary examination are pathognomonic for this disease. The present report describes some abnormalities seen on magnetic resonance imaging (MRI) evaluation of a series of SM patients and discusses their etiopathogenesis. Methods: This study evaluated SM patients at the time of their diagnosis. These patients...

Date: 2012   |   Origin: Oasisbr

Ganglioglioma: comparison with other low-grade brain tumors

Brainer-Lima,Paulo Thadeu; Brainer-Lima,Alessandra Mertens; Azevedo-Filho,Hildo Rocha

METHOD: Forty-two patients with low-grade brain tumor and refractory epilepsy were studied. The mean age was 22.3 years. They were divided into two groups: Group A, patients with ganglioglioma (n=19) and group B, patients with other low-grade tumors (n=23) (14 astrocytoma, 6 oligodendroglioma, 2 dysembryoplastic neuroepithelial tumor, and 1 xanthoastrocytoma). RESULTS: Age at seizure’s onset was 7 years or less...

Date: 2006   |   Origin: Oasisbr

Mapeamento da área motora durante a cirurgia de tumor intracraniano: fatores qu...

Brainer-Lima,Paulo Thadeu; Brainer-Lima,Alessandra Mertens; Brandt,Carlos Texeira; Carneiro,Geraldo Sá; Azevedo,Hildo C.

O mapeamento com estimulação direta do córtex cerebral foi utilizado quando o tumor estava próximo ou infiltrava o lobo central. OBJETIVO: Avaliar interferências na técnica de estimulação eletrica direta do córtex e substância branca, sob anestesia geral, durante cirurgia para tumor cerebral relacionado ao lobo central. MÉTODO: Foram estudados 42 pacientes operados de junho de 2000 a junho de 2003. Os fatores q...

Date: 2005   |   Origin: Oasisbr

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