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Lung Adenocarcinoma: The Diagnostic Importance of Echocardiography

Ferreira Neves, I; Garcia Brás, P; Coelho, P; Calvinho, P; Branco, L


Microvascular Dysfunction Is Associated With Impaired Myocardial Work in Obstru...

Garcia Brás, P; Aguiar Rosa, S; Cardoso, I; Branco, L; Galrinho, A; Valentim Gonçalves, A; Thomas, B; Viegas, JM; Fiarresga, A; Branco, G; Pereira, R

Background Two-dimensional speckle tracking echocardiography has been shown to correlate with microvascular dysfunction, a hallmark of hypertrophic cardiomyopathy (HCM). We hypothesized that there is an association between myocardial work and left ventricular ischemia, with incremental value to global longitudinal strain, in patients with HCM. Methods and Results We performed a prospective assessment of patient...


Impact of Repaired Aortic Coarctation in Left Ventricular Myocardial Work

Timóteo, AT; Branco, L; Galrinho, A; Rio, P; Sousa, L; Cruz Ferreira, R

Aims: Myocardial strain analysis enables more precise assessment of cardiac performance but is relatively load dependent. New tools have been developed with afterload adjustment. Our objective was to assess myocardial work (MW) in patients with repaired aortic coarctation (rACo). Methods: Prospective study of consecutive patients with rACo who underwent a routine transthoracic echocardiogram in 2018 and 2019 at...


Blunted Coronary Flow Velocity Reserve is Associated With Impairment in Systoli...

Aguiar Rosa, S; Rocha Lopes, L; Branco, L; Galrinho, A; Fiarresga, A; Thomas, B; Brás, P; Gonçalves, A; Cardoso, I; Papoila, A; Alves, M; Rio, P

Background Coronary microvascular dysfunction constitutes an important pathophysiological feature in hypertrophic cardiomyopathy (HCM). We aimed to assess the association between impaired coronary flow velocity reserve (CFVR) and ventricular systolic function and functional capacity. Methods Eighty-three patients with HCM were enrolled in this prospective cohort study. Patients underwent echocardiogram to evalu...


Late Gadolinium Enhancement in the Left Ventricular Wall Is Associated with Atr...

Castelo, A; Aguiar Rosa, S; Fiarresga, A; Jalles, N; Vaz Ferreira, V; Garcia Brás, P; Branco, L; Oliveira, M; Cruz Ferreira, R

Purpose: Atrial fibrillation (AF) is the most common arrhythmia in patients with hypertrophic cardiomyopathy (HCM). The aim of this study was to evaluate the relation between AF and left ventricular (LV) late gadolinium enhancement (LGE). Methods: 55 patients with HCM were retrospectively included. Patients were divided in HCM with AF and HCM without AF. Baseline clinical, echocardiographic and cardiovascular m...


Ambipolar Pentacyclic Diamides with Interesting Electrochemical and Optoelectro...

Burke, aNTHONY; Marques, CS; Ramalho, JP; Branco, L; Gago, Sandra; Cruz, Hugo; Lawrence, S; Morgado, J

Developing organic semiconductors for organic thin film transistors (OTFT) and optoelectronic applications is a challenge. We developed highly crystalline pentacyclic diimides (3) and (4) which showed good OTFT and OLED potential and energy gaps of 2.60 eV and 2.54 eV. They exhibited interesting photo and eletroluminescence activity. Both compounds showed good quantum yields (0.56 for (3) and 0.60 for (4)).


Causa Inesperada de Disfunção Sistólica em Octogenária

Pereira-da-Silva, T; Galrinho, A; Branco, L; Antunes, E; Cruz Ferreira, R


Metal complexes of dipyridine hexaaza macrocycles. Structural differences betwe...

Branco, L; Costa, J; Delgado, R; Drew, MGB; Felix, V; Goodfellow, BJ

The hexaaza macrocycles 3,6,14,17,23,24-hexaazatricyclo[ 17.3.1.1(8,12)]tetracosa-1(23), 8,10,12(24), 19,21-hexaene ([18]py(2)N(4)) and 3,7,15,19,25,26-hexaazatricyclo[19.3.1.1(9,13)]hexacosa-1(25), 9,11,13(26), 21,23-hexaene ([20]py(2)N(4)) were synthesised. The protonation constants of both compounds and the stability constants of their complexes with a wide range of metal ions (Mn2+, Ni2+, Cu2+, Zn2+, Cd2+, ...


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