178 documents found, page 1 of 18
Genossensores Eletroquímicos de Identificação de Espécies Vegetais: Foco no Cas...
Morais, Stephanie; Pereira, Eduarda; Castanheira, Michelle; Santos, Marlene; Domingues, Valentina; Deleure-Matos, Cristina; Barroso, FátimaNeste trabalho, foram desenvolvidos dois genossensores eletroquímicos descartáveis para a identificação de plantas baseado na reação de hibridização entre duas cadeias de ADN complementares de duas espécies de plantas: Erica arborea (urze) e Castanea sativa (castanheiro). Analisando bases de dados públicas, foram selecionados dois pares de sequências especificamente cortadas e desenhadas para identificar o ADN ...
Design of innovative electrochemical genosensors for honey fraud and quality de...
Morais, Stephanie L.; Castanheira, Michelle; Pereira, Eduarda; Santos, Marlene; Domingues, Valentina F.; Delerue-Matos, Cristina; Barroso, M. FátimaEnsuring food safety has become a concern for companies, consumers and the government alike, due to the increase of fraudulent and/or adulterated food products found in the global market [1,2]. Some common fraudulent strategies include mislabelling a product's geographical origin and blending it with lower-grade substances [3]. Among the frequently adulterated food products there is honey. Honey is a highly sou...
Warfarin pharmacogenomics: Designing electrochemical DNA-based sensors to detec...
Barbosa, Tiago; Morais, Stephanie L.; Pereira, Eduarda; Magalhães, Júlia M. C. S.; Domingues, Valentina F.; Ferreira-Fernandes, Hygor; Pinto, GiovannyThe CYP2C9 enzyme is involved in the metabolism of warfarin. The CYP2C9 gene harbors several single-nucleotide polymorphisms (SNPs), including CYP2C9*2 (rs1799853), which is known to affect warfarin’s therapeutic response. So, it is important to develop analytical tools capable of genotyping these SNPs to adjust warfarin’s therapeutic outcomes. In this work, an electrochemical DNA-based sensor was constructed a...
Comparison between anthropometric equipment and scanners in hand measurement
Filho, P. C. Anacleto; Silva, Lincoln da; Castellucci, H. I.; Rodrigues, Matilde; Pereira, Eduarda; Pombeiro, Ana; Colim, Ana; Carneiro, PaulaAnthropometric studies have influenced the design of apparel, accessories, medical prostheses, equipment, workstations, and tools. Particularly, hand anthropometry is related to safety and adequacy of hand tools and devices. Different equipment and methods can be used to obtain body measurements with different precision and reliability levels. However, precision and reliability are not the only aspects to be co...
Ensuring food safety: electrochemical genosensors for the authentication of pla...
Morais, Stephanie L.; Pereira, Eduarda; Castanheira, Michelle; Santos, Marlene; Domingues, Valentina; Delerue-Matos, Cristina; Barroso, M. FátimaHoney is a high-quality and natural ingredient often consumed because of its unique sweet taste and multiple therapeutic and nutritional benefits. These properties are normally intrinsically connected to the regional flora from which the plant pollen is harvested. Hence, the botanical and geographical origins of honeys play a substantial role in the end product's composition. With the recent interest in natural...
Plant honey origin authentication: Use of electrochemical genosensors for food ...
Morais, Stephanie; Pereira, Eduarda; Castanheira, Michelle; Santos, Marlene; Domingues, Valentina; Delerue-Matos, Cristina; Barroso, M. FátimaHoney is a natural high-quality food product consumed worldwide due to its diverse nutritional profile and beneficial medical properties. These factors, along with honey’s unique sweet taste and odour, make it one of the most popular products for a healthy diet. Nevertheless, food fraud is an increasing problem with various impacts on the economy, health, and in the environment, as honey prices are established ...
Enhancing the detection of Dinophysis spp. using electrochemical genosensors
Pereira, Eduarda; Silva, Aurora; Morais, Stephanie L.; Costa-Rama, Estefanía; Moreira, Patrícia R.; Fraga-Corral, M.; Torrado, Ana M.Background: Harmful algal blooms (HABs) pose a significant threat to the environment and public health. These blooms are defined by an accumulation of microscopic algae in water, and they can occur in lakes, rivers, estuaries, or coastal areas. Factors like the unregulated runoff of agricultural and industrial wastes into the aquatic environment [1] are believed to have transformed these ecosystems into favorab...
Warfarin genetic biomarkers in VKORC1 and CYP2C9*2 genes: Advancing personalize...
Moreira, Tiago; Pereira, Eduarda; Costa, Inês F.; Sousa, António J.S.F.; Morais, Stephanie L.; Ferreira-Fernandes, Hygor; Pinto, Giovanny R.Background: The genetic variants of vitamin K epoxide reductase complex (VKORC1) and in the cytochrome CYP2C9*2 genes have been identified to influence the anticoagulant warfarin and influence its plasmatic levels. Therefore, the pharmacogenetic information on these genes is useful for reducing warfarin adverse reaction [1]. Objectives: This work addresses the development of disposable electrochemical genosenso...
Integrated Use of Bioaccumulation, Genotoxic, and Haematological Endpoints to A...
Mieiro, Cláudia Leopoldina; Coelho, João; Reis, Ana; Castro, Diana; Figueira, Paula; Martinho, Filipe; Pardal, Miguel; Pereira, Eduarda; Pacheco, MárioBiosorption successfully remediates saline water contaminated with legacy contaminants, but its effects on the health of marine organisms remain unclear. Therefore, our aim was to address this knowledge gap with data on the accumulation ability, as well as the cytogenetic and biochemical effects in turbot (Scophthalmus maximus). To this end, we exposed turbot for seven days to a mixture of remediated metals (Re...
Antarctic toothfish Dissostichus mawsoni as a bioindicator of trace and rare ea...
Queirós, José P.; Machado, João F.; Pereira, Eduarda; Bustamante, Paco; Carvalho, Lina; Soares, Eugénio; Stevens, Darren W.; Xavier, José CarlosThe Antarctic toothfish Dissostichus mawsoni is a Southern Ocean long-lived top predator which is regularly captured on an annual fishery operating in the region. By its biological and ecological characteristics, it is a potential bioindicator for the concentrations of trace and rare earth elements in the Antarctic. As these elements are mainly transferred through the diet and a deficiency or excess of these el...