Introduction: Sporadic Creutzfeldt-Jakob disease (sCJD) is the most frequent of human prion diseases, with an estimated incidence of 1 case per million / habitants per year. Clinical manifestations include multidomain cognitive impairment with pyramidal, extrapyramidal and/or cerebellar signs. It is a rapidly progressive and fatal disease. Our aim was to do a sociodemographic, clinical and progression evaluatio...