17 documents found, page 1 of 2
Design and Experimental Evaluation of a New RNA-FISH Probe to Detect and Identi...
Arantes, S; Branco, P; Caldeira, A TeresaPaenibacillus, rod-saped gram-positive endospores forming aerobic or facultative anaerobic bacteria, colonize diverse ecosystems and are involved in the biodegradation of cultural heritage assets. Biodeteriogenic microorganisms can be easily detected/identified by ribonucleic acid- fluorescent in situ hybridization RNA-FISH with specific probes. In this work, probes designed in silico were analyzed to calculate...
Heterogeneous impacts of mobility restrictions on air quality in the State of S...
Cirqueira, SSR; Rodrigues, PF; Branco, P; Vormittag, E; Nunes, R; Anastacio, AVB; Veras, M; Sousa, SIV; Saldiva, PHNAir quality in the State of Sao Paulo was evaluated during the first general State plan of mobility restrictions due to the COVID-19 pandemic (24th March to May 31, 2020). Nitrogen dioxide (NO2), ozone (O-3), particulate matter PM10 and PM2.5 and sulphur dioxide (SO2) concentrations were assessed in cities of the Sao Paulo State with a monitoring station and compared to historical data. Linear regression models...
ON-FIELD PERFORMANCE TEST AND CALIBRATION OTWO COMMERCIALLY AVAILABLE LOW-COST ...
Chojer, H; Branco, P; Martins, F; Sousa, SIVThe use of low-cost devices for air quality monitoring is rapidly growing, and the reason behind the growth might (at least partially) be the real-time monitoring at a lower fixed and operating cost, ease of use and portability. Nevertheless, the poor data reliability of low-cost sensors (LCS) remains a consid-erable challenge, especially when deployed in real-world conditions. This study aimed to evaluate and ...
A simple procedure for detecting Dekkera bruxellensis in wine environment by RN...
Branco, P; Candeias, A; Caldeira, A Teresa; Pérez, MDekkera bruxellensis, considered the major microbial contaminant in wine production, produces 4-ethylphenol, a cause of unpleasant odors. Thus, identification of this yeast before wine spoilage is crucial. Although challenging, it could be achieved using a simple technique: RNA-FISH. To reach it is necessary to design probes that allow specific detection/identification of D. bruxellensis among the wine microorg...
Anemia and Iron Deficiency Diagnosis, Management and Treatment in Chronic Kidne...
Ferreira, A; Farinha, A; Macedo, A; Robalo Nunes, A; Lopes, J; Branco, P; Ponce, P; Neto, RBackground: Anemia is a common complication of Chronic Kidney Disease (CKD), in which iron deficiency’s (ID) role is frequently underrated. In CKD, anemia has been associated with higher morbidity and lower quality of life. Nonetheless, reported treatment rates of anemia in CKD are low and guidelines’ variability and/or absence for its management and treatment may be preventing patients from receiving optimal t...
Hyperkalemia and management of renin-angiotensin-aldosterone system inhibitors ...
Fonseca, C; Brito, D; Branco, P; Frazão, JM; Silva-Cardoso, J; Bettencourt, PIntroduction and Objectives: Renin-angiotensin-aldosterone system inhibitors (RAASi) are the cornerstone of treatment of heart failure with reduced ejection fraction (HFrEF). RAASi optimization in real-life care is challenged by hyperkalemia, a potentially fatal adverse event, which can necessitate downtitration or discontinuation of RAASi and negatively impact survival in HFrEF. The literature on this problem ...
A 2018 overview of diuretic resistance in heart failure
Jardim, S; Ramos dos Santos, L; Araújo, I; Marques, F; Branco, P; Gaspar, A; Fonseca, CAbstract Heart failure is a disease with high direct and indirect costs. Current treatment includes drugs that alter disease progression and drugs that to improve symptoms. Loop diuretics are the cornerstone of congestion relief for acute management, as well as for chronic stabilization. In heart failure patients, maximal diuretic response is reduced by many individual factors. Diuretic resistance is defined as...
Effect of empagliflozin beyond glycemic control: Cardiovascular benefit in pati...
Monteiro, P; Aguiar, C; Matos, P; Silva-Nunes, J; Birne, R; Branco, P; Calado, J; Melo, M; Polónia, JThe prevalence of type 2 diabetes (T2D) continues to increase, and its association with cardiovascular (CV) disease has led to the inclusion of CV endpoints in clinical trials on the treatment of T2D. This article explores the various trials already performed and under development in this field, with particular focus on the EMPA-REG OUTCOME trial. In this trial, empagliflozin, a sodium-glucose co-transporter 2 ...
Specificity and performance evaluation of a novel RNA-FISH probe for the identi...
Branco, P; Arantes, S; Candeias, A; Caldeira, A T; González-Pérez, MTo distinguish Rhodotorula sp., from other microorganisms that produce the same type of alterations on CH materials, proper identification methods must be applied. RNA-fluorescence and in situ hybridization (RNA-FISH) has the potential to specifically identify the target microorganism of interest in complex microbial communities (it is based on hybridization of fluorescently-labeled oligonucleotide probes targe...
Effect of Empagliflozin Beyond Glycemic Control: Cardiovascular Benefit in Pati...
Monteiro, P; Aguiar, C; Matos, P; Silva-Nunes, J; Birne, R; Branco, P; Calado, J; Melo, M; Polónia, JThe prevalence of type 2 diabetes (T2D) continues to increase, and its association with cardiovascular (CV) disease has led to the inclusion of CV endpoints in clinical trials on the treatment of T2D. This article explores the various trials already performed and under development in this field, with particular focus on the EMPA-REG OUTCOME trial. In this trial, empagliflozin, a sodium-glucose co-transporter 2 ...