69 documents found, page 1 of 7

Toward a global repository of insect traits (GRIT)

ABSTRACT: The pace of biodiversity loss outstrips our ability to conserve Earth's most diverse group of named species—the insects (Arthropoda: Insecta). We increasingly rely on trait-based metrics to understand how insects respond to and affect their environment. Traits provide insights that aid conservation assessment and planning. Yet, we lack a centralised trait database for insects, hampering insights that ...

Exposure of human glioblastoma cells to thimerosal inhibits the thioredoxin sys...

Glioblastoma multiforme (GBM) is the most common, aggressive, and fatal primary malignant brain tumor in adults. The therapeutic efficacy of temozolomide (TMZ) is limited owing to frequent treatment resistance. The latter is in part related to the overexpression of redox systems such as the thioredoxin system. This system is fundamental for cell survival and proliferation, regulating hypoxia inducible factor-1a...

Objective structured clinical/practical examination (OSC/PE) in pharmaceutical ...

Objective Structured Clinical/Practical Examination (OSC/PE) in Pharmaceutical ...

Guiding principles of interaction and usability for the development of a Archit...

The Cycle of Linen is an ancient tradition of linen making in Portugal that is practically extinct but which survives in the Caramulo mountain range, thanks to the skill and resilience of the artisans of the AmaCastelões association.This article describes the participant observation phase of a doctoral research project in design which focuses on identifying specialities and specificities that could contribute f...

Interaction of Polycyclic Aromatic Hydrocarbon compounds in fish primary hepato...

Polycyclic Aromatic Hydrocarbons (PAHs) are persistent pollutants normally found in the environment as complex mixtures. Although several individual PAHs are classified as mutagenic and carcinogenic pollutants, the interaction effects between compounds in a mixture may trigger different toxicological mechanisms and, consequently, yield different effects to organisms which are not accounted for in risk assessmen...

Nanoplastics activate a TLR4/p38-mediated pro-inflammatory response in human in...

The crescent presence of nanoplastics in the environment raises concerns regarding their potential impact on health. This study exposed human colon adenocarcinoma cells (HT29) and microglia cells (N9) to nanoplastics (25 nm, 50 nm, and 100 nm Polystyrene) to investigate their inflammatory responses, which are vital for body's defence. Although cytotoxicity remained generally low, HT29 cells exhibited a notable ...

Interaction of polycyclic aromatic hydrocarbon compounds in fish primary hepato...

Polycyclic Aromatic Hydrocarbons (PAHs) are persistent pollutants normally found in the environment as complex mixtures. Although several individual PAHs are classified as mutagenic and carcinogenic pollutants, the interaction effects between compounds in a mixture may trigger different toxicological mechanisms and, consequently, yield different effects to organisms which are not accounted for in risk assessmen...

Editorial : redox-signaling in neurodegenerative diseases : biomarkers, targets...

Nanoplastics activate a TLR4/p38-mediated pro-inflammatory response in human in...

The crescent presence of nanoplastics in the environment raises concerns regarding their potential impact on health. This study exposed human colon adenocarcinoma cells (HT29) and microglia cells (N9) to nanoplastics (25 nm, 50 nm, and 100 nm Polystyrene) to investigate their inflammatory responses, which are vital for body's defence. Although cytotoxicity remained generally low, HT29 cells exhibited a notable ...