Omega 3-docosahexaenoic acid (DHA) and vitamin E Delta-tocotrienol (Delta-T3) are extensively studied as protective nutrients against cancer development. Little is known about the biological mechanisms targeted by these bioactive molecules on lipid droplet (LD) biogenesis, an important breast cancer aggressiveness marker, and the occurrence of lipophagy in breast cancer cells. The aim of this study was to inves...
The implication of inflammation in pathophysiology of several type of cancers has been under intense investigation. Omega-3 fatty acids can modulate inflammation and present anticancer effects, promoting cancer cell death. Pyroptosis is an inflammation related cell death and so far, the function of docosahexaenoic acid (DHA) in pyroptosis cell death has not been described. This study investigated the role of DH...
Dissertação (mestrado)—Universidade de Brasília, Faculdade de Ciências da Saúde, Programa de Pós-Graduação em Nutrição Humana, 2015.; O ácido docosahexaenóico (DHA) possui efeito antitumoral em células de câncer de mama pela diminuição da proliferação celular e pelo aumento da morte por apoptose. Já o ácido araquidônico (AA) está relacionado ao crescimento e à progressão tumoral. Nenhuma pesquisa até o momento ...
Monografia (graduação)—Universidade de Brasília, Faculdade de Ciências da Saúde, Departamento de Nutrição, 2012.; Submitted by Letícia Gomes T. da Silva (leticiagomes.silva.07@gmail.com) on 2013-10-15T17:06:59Z No. of bitstreams: 1 2012_BeatrizChristinaLuzete.pdf: 232163 bytes, checksum: 7222161def1cce46646066d4a63e4839 (MD5); Approved for entry into archive by Luanna Maia(luanna@bce.unb.br) on 2013-10-16T16:36...