12 documents found, page 1 of 2
Identification and determination of the inulin content in the roots of the Nort...
Pontes, Ana Georgina Oliveira; Silva, Karine Lima; Fonseca, Said Gonçalvez da Cruz; Soares, Arlete Aparecida; Feitosa, Judith Pessoa de AndradeA polysaccharide was extracted from the roots of Pombalia calceolaria, a plant used in folk medicine in Northeastern Brazil, by decoction followed by precipitation with methanol, yielding a concentration of 13.0% w/w, and purification with acetone. The molar mass peak was estimated to be 4.0 × 103 Da using gel permeation chromatography (GPC). Polarized light photomicrography of histological sections revealed th...
New flavone and other compounds from Tephrosia egregia: assessing the cytotoxic...
Teixeira, Maria V. S.; Lima, Jefferson Q.; Pimenta, Antônia T. A.; Silva, Francisca R. L. da; Oliveira, Maria da Conceição F. de; Pereira, Italo G.The organic extracts from stems, roots and leaves of Tephrosia egregia Sandwith, Fabaceae, provided anew flavone, 5-hydroxy-8-(1 ,2 -epoxy-3 -hydroxy-3 -methylbutyl)-7-methoxyflavone (1), in additionto eleven known compounds: pongaflavone (2), praecansone B (3), 12a-hydroxyrotenone (4), praecan-sone A, 2 ,6 -dimethoxy-4 ,5 -(2 ,2 -dimethyl)-pyranochalcone, pongachalcone, maackiain, -sistosteroland its glucoside...
7-epi-griffonilide, a new lactone from Bauhinia pentandra: complete 1H and 13C ...
Almeida, Macia Cleane Soares de; Souza, Luciana G. S.; Ferreira, Daniele A.; Pinto, Francisco C. L.; Oliveira, Débora R. de; Santiago, Gilvandete M. P.A new lactone, 7-epi-griffonilide (1), and six known compounds, 2, 3a - 3c, 4a and 4b, were isolated from the leaves of Bauhinia pentandra (Fabaceae). The structures elucidation of 1 and 2 were based on detailed 2D NMR techniques and spectral comparison with related compounds, leading to complete assignment of the 1H and 13C NMR spectra.
Activity of Fabaceae species extracts against fungi and Leishmania : vatacarpan...
Santana, Dandara Braga; Costa, Raphaella Correia da; Araújo, Renata Mendonça; Paula, José Elias de; Silveira, Edilberto Rocha; Braz-Filho, RaimundoLeishmaniasis and fungal infection treatment efficacy is limited by toxicity and ever increasing resistance to available drugs, requiring development of alternative compounds. The richness of Cerrado plant antimicrobial secondary metabolites justifies screening of Fabaceae species extracts: Enterolobium ellipticum Benth., Sclerolobium aureum (Tul.) Baill. and Vatairea macrocarpa(Benth.) Ducke, against Leishmani...
Clusiaxanthone and tocotrienol Series from Clusia pernambucensis and their anti...
Silva, Everton Macêdo; Araújo, Renata M.; Freire-Filha, Lindomar G.; Silveira, Edilberto R.; Lopes, Norberto P.; Paula, José Elias deA análise fitoquímica do extrato acetato de etila da casca do caule de Clusia pernambucensis G. Mariz, Clusiaceae, uma espécie do Cerrado brasileiro, conduziu ao isolamento e caracterização completa de uma nova xantona, 1,7-dihidróxi-2-(3-metil-2-butenil)-6',6'-dimetilpirano(2',3':3,4) xantona, denominada clusiaxantona. Quatro tocotrienóis ainda não relatados nesta espécie também foram isolados. Um derivado foi...
Spirostanol glucosides from the leaves of Cestrum laevigatum L.
Ribeiro, Paulo Riceli Vasconcelos; Araújo, Ana Jérsia; Costa-Lotufo, Letícia Veras; Braz-Filho, Raimundo; Nobre Júnior, Hélio VitorianoTwo new steroidal saponins, (25R)-spirost-5-ene-3β,26β-diol 3-O-α-l-rhamnopyranosyl-(1 → 4)-α-l-rhamnopyranosyl-(1 → 4)-[(1 → 2)-α-l-rhamnopyranosyl]-β-d-glucopyranoside (1) and (25R)-spirost-6-ene-3β,5β-diol 3-O-α-l-rhamnopyranosyl-(1 → 4)-α-l-rhamnopyranosyl-(1 → 4)-[(1 → 2)-α-l-rhamnopyranosyl]-β-d-glucopyranoside (2), along with the known diosgenin 3-O-α-l-rhamnopyranosyl-(1 → 4)-α-l-rhamnopyranosyl-(1 → 4)...
New terpenoids from Croton limae (Euphorbiaceae)
Sousa, Antonio H.; Silva Junior, José N.; Guedes, Maria L. S.; Braz-Filho, Raimundo; Costa-Lotufo, Letícia V.; Araújo, Ana J.; Silveira, Edilberto R.An asymmetrical dimer of kaurane diterpene and monoterpene and four novel diterpenes were isolated from the roots of Croton limae, along with kaempferol-3-O-glucoside, ombuin- 3-O-rutinoside and acetyl aleuritolic acid. The cytotoxic activity of the kaurane diterpene was evaluated against colorectal adenocarcinoma (HCT-116), ovarian carcinoma (OVCAR-8) and glioma (SF-295) cell lines, exhibiting IC50 values of 7...
Solanidane and iminosolanidane alkaloids from solanum campaniforme
Torres, Maria Conceição M.; Jorge, Roberta Jeane B.; Ximenes, Rafael M.; Alves, Natacha Teresa Queiroz; Santos, João Victor de A.; Marinho, Aline D.From the leaves of Solanum campaniforme (Solanaceae), eight solanidane alkaloids were isolated, four of which contain a p-hydroxyphenylethylamine unit. Their structures were established as: 22b,23b-epoxysolanida- 1,4-dien-3-one; 22a,23a-epoxy-10-epi-solanida-1,4,9-trien-3-one; 22a,23a-epoxy-solanida-4- en-3-one; 22b,23b-epoxy-solanida-4-en-3-one; (E)-N-[80(4-hydroxyphenyl)ethyl]-22a,23a-epoxy-solanida-1, 4,9-tr...
Trachylobane and kaurane diterpenes from Croton floribundus Spreng
Uchôa, Paula Karina S.; Silva Jr., José Nunes da; Silveira, Edilberto Rocha; Lima, Mary Anne S.; Braz-Filho, Raimundo; Costa-Lotufo, Letícia VerasA new trachylobane diterpene ent-trachyloban-18,19-diol (1) was isolated from root bark of Croton floribundus, along with known diterpenes ent-trachyloban-19-oic acid (2), 15b-hydroxy-ent-trachyloban-19-oic acid (3), ent-trachyloban-19-ol (4), ent-kaur-16-en- 19-oic acid (5), ent-kaur-16-ene-6a,19-diol (6) and ent-16a-hydroxykaur-11-en-19-oic acid (7). ent-trachyloban-18,19-diol (1) was submitted to derivatizat...
Glicoalcaloides antifúngicos, flavonoides e outros constituintes químicos de So...
Pinto, Francisco das Chagas L.; Uchoa, Daniel Esdras de Andrade; Silveira, Edilberto Rocha; Pessoa, Otília Deusdênia Loiola; Braz-Filho, RaimundoTwo glycoalkaloids: solamargine and solasonine; three flavonoids: tiliroside, 7-O-α-L-ramnopyranosyl-kaempferol and 3-O-[ß-D-glucopyranosyl-(1→6)-α-L-ramnopyranosyl]-7- O-α-L-ramnopyranosyl-kaempferol, in addition to the tripeptide Leu-Ile-Val, the aminoacid proline and the eicosanoic acid were isolated from Solanum asperum (Solanaceae). The structures of all compounds were determined by interpretation of their...