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Retinal OCT speckle as a biomarker for glaucoma diagnosis and staging

Vaz, Pedro G.; Brea, Luisa Sanchez; Silva, Vânia Bastos; van Eijgen, Jan; Stalmans, Ingeborg; Cardoso, João; van Walsum, Theo; Klein, Stefan

This paper presents a novel image analysis strategy that increases the potential of macular Optical Coherence Tomography (OCT) by using speckle features as biomarkers in different stages of glaucoma. A large pool of features (480) were computed for a subset of macular OCT volumes of the Leuven eye study cohort. The dataset contained 258 subjects that were divided into four groups based on their glaucoma severit...


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