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Development of an oral suspension containing dry extract of Aleurites moluccanu...

Donald,Richie Mac; Camargo,Sabrina Santana; Meyre-Silva,Christiane; Quintão,Nara Lins Meira; Cechinel Filho,Valdir; Bresolin,Tania Mari Bellé

Abstract Aleurites moluccanus L. (Willd.), Euphorbiaceae, is a tree that is native to Indonesia and India. Various parts of this tree are commonly used in traditional medicine to treat pain, fever, inflammation, hepatitis, gastric ulcer and other ailments. An oral suspension containing dried extract of A. moluccanus was developed and in vivo anti-inflammatory activity was evaluated. Extract 100 and 50 mg/ml loa...

Date: 2016   |   Origin: Oasisbr

Simultaneous determination of four phenolic compounds in extracts of aerial par...

Dutra,Daniela Maes; Barth,Cristiane da Silva; Block,Luciana Catia; Quintão,Nara Lins Meira; Couto,Angélica Garcia; Cechinel Filho,Valdir

Among other applications, Ipomoea pes-caprae is popularly used to treat jellyfish stings, supporting the development of a product for dermatological use. Hydroethanolic spray-dried extract was chosen for the further development of phytomedicines, and a stability-indicative HPLC-UV method was developed and validated for the determination of isoquercitrin and isochlorogenic acids A, B and C. The method was develo...

Date: 2014   |   Origin: Oasisbr

Validation of an hplc method for the determination of 1,7-dihydroxy-2,3-methyle...

Klein-Júnior,Luiz Carlos; Andrade,Sérgio Faloni de; Cechinel-Filho,Valdir; Bresolin,Tania Mari Bellé

Polygala cyparissias is a plant widespread in Southern Latin America. Recently, we demonstrated the gastroprotective activity of the extract, as well as for one of the isolated metabolites-1,7-dihydroxy-2,3-methylenedioxyxanthone (MDX). In this study, a HPLC method for the quantification of MDX was validated. The HPLC method was linear (0.5-24 µg mL-1 of MDX) with good accuracy, precision and robustness. The co...

Date: 2014   |   Origin: Oasisbr

Pharmaceutical use of galactomannans

Silveira,Joana Léa Meira; Bresolin,Tania Mari Bellé

The pharmaceutical use of galactomannans from different sources, commercial and noncommercial, has been extensively studied over the past decade. Galactomannans show potential in the global trend towards the use of more plant-based products for ecological motives, and their production and application do not cause pollution or disturb the ecosystem. There is a variety of galactomannan sources and various pharmac...

Date: 2011   |   Origin: Oasisbr

Comparação do crescimento de Saccharomyces boulardii em fermentador por batelad...

Muller,José Luis; Protti,Karina Luvizutto; Machado,Marina da Silva; Lacerda,Leo Lynce Valle de; Bresolin,Tania Mari Bellé; Podlech,Pablo Sanchez

Os fermentadores tipo air lift oferecem vantagens tais como: eficiente homogeneização dos componentes, baixo cisalhamento e economia de energia, pois o meio é agitado pelo processo de aeração, sem necessidade de agitação mecânica. O objetivo deste trabalho foi analisar a cinética de crescimento de Saccharomyces boulardii neste fermentador, com aeração de 1 e 1,5 vvm (volume de ar por volume de meio, por minuto)...

Date: 2007   |   Origin: Oasisbr

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