3 documents found, page 1 of 1
Influence of lysosomal protease sensitivity in the immunogenicity of the antitu...
Rodrigues, Mariane A.D.; Pimenta, Marcela V.; Costa, Iris M.; Zenatti, Priscila P.; Migita, Natacha A.; Yunes, José A.; Rangel-Yagui, Carlota O.Made available in DSpace on 2021-06-25T10:35:17Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Ministério da Ciência, Tecnologia, Inovações e Comunicações; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); L-asparaginase (ASNase) from Escherichia ...
Global analysis of erythroid cells redox status reveals the involvement of Prdx...
Romanello, Karen S.; Teixeira, Karina K.L.; Silva, João Pedro M.O.; Nagamatsu, Sheila T.; Bezerra, Marcos André C.; Domingos, Igor F.Made available in DSpace on 2019-10-06T16:08:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); β-thalassemia is a worldwide distributed monogenic red cell disorder, characterized by an absent or reduced beta globin chain synthesis. The unbalance of alpha-gamma chain and the presence of pathological free iron promote severe oxidative d...
Catalytic Thr or Ser Residue Modulates Structural Switches in 2-Cys Peroxiredox...
Tairum, Carlos A. [UNESP]; Santos, Melina Cardoso [UNESP]; Breyer, Carlos A. [UNESP]; Ryan Geyer, R.; Nieves, Cecilia J.; Portillo-Ledesma, StephanieMade available in DSpace on 2018-11-26T17:06:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-09-15; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Typical 2-Cys Peroxiredoxins (2-Cys Prxs) reduce hydroperoxides with extraordinary rates due to an active site composed of a catalytic triad, containing a peroxidatic cysteine (CP), an Arg, and a Thr (or Ser). 2-Cys Prx are involved in proce...