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Bacteriocin dynamics in Enterococcus faecium and Enterococcus lactis: implicati...

Almeida-Santos, Ana C.; Tedim, Ana P.; Duarte, Bárbara; Brilhante, Michael; Coque, Teresa M.; Novais, Carla; Freitas, Ana R.; Peixe, Luísa

Background: Enterococcus faecium-Efm and E.lactis-Elts (former Efm-cladeB) colonize the human gut, with Efm also being a leading hospital-pathogen. Dynamics influencing strain dominance in competitive environments (e.g., infection/colonization) are not fully understood, but bacteriocins may provide competitive advantage to clinical Efm or commensal Elts strains. Objective: We explored bacteriocin content of con...

Date: 2024   |   Origin: Scientific Letters

Oxa-181-producing extraintestinal pathogenic escherichia coli sequence type 410...

Brilhante, Michael; Menzes, Juliana; Belas, Adriana; Feudi, Claudia; Schwarz, Stefan; Pomba, C.; Perretena, Vincent

Two multidrug-resistant and carbapenemase-producing Escherichia coli clones of sequence type 410 were isolated from fecal samples of a dog with skin infection on admission to an animal hospital in Portugal and 1 month after discharge. Whole-genome sequencing revealed a 126,409-bp Col156/IncFIA/IncFII multidrug resistance plasmid and a 51,479-bp IncX3 blaOXA-181-containing plasmid. The chromosome and plasmids ca...


Unveiling clones and integrons dynamics associated with carbapenemase-producing...

Botelho, João; Grosso, Filipa; Sousa, Clara Cecília Santana; Brilhante, Michael; Rocha, Catarina; Peixe, Luísa

[Excerpt] Particular epidemic lineages (e.g. 235, 111, ST175 and 244) are associated with carbapenemase-producing P. aeruginosa (CPPA) isolates causing infections. Due to limited therapeutic options and possible carbapenemase spread, CPPA infections are of great concern. Nevertheless, the occurrence, genetic background and clonal dynamics over a long period of time of CPPA strains in Portuguese hospitals are un...


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