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Real-World Experience with Avacopan in ANCA-Associated Vasculitis in Portugal

Oliveira Correia, Sofia; Laranjinha, Ivo; Nogueira, Estela; Cunha, Anita; Tenazinha, Catarina; Pinto, Helena; Ferreira, Inês; Fernandes Serodio, João

Introduction: Avacopan, a selective C5a receptor inhibitor, has emerged as a potential corticosteroid-sparing treatment in ANCA-associated vasculitis (AAV). This study aims to evaluate its real-world efficacy and safety in Portuguese patients with active AAV. Methods: We conducted a multicenter retrospective analysis of 15 adult patients with newly diagnosed or relapsing AAV treated with avacopan across nine ac...


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