3 documents found, page 1 of 1
Quintas com Piano - Jovens Solistas da Metropolitana
Ceia, Carolina; Cunha, Alessio; Mata, Marta; Rocha, Francisca; Pinho, Matilde; Pimenta, Carolina; Brito, Daniela; Moniz, Leonor; Tomás, BeatrizBrochura de sala do concerto realizado pelos Jovens Solistas da Metropolitana a 7 de Novembro de 2019 no ESTÚDIO ABERTO, SEDE da METROPOLITANA em Lisboa no âmbito da Temporada 2019/2020 da Metropolitana. O programa do concerto foi preenchido com obras do Rota, Beethoven, Reger, Glazunov e Grieg. Desenvolvendo uma ponte pedagógica inédita entre a prática e o ensino musical, a ANSO é a única escola do país que fo...
CDK1 Prevents Unscheduled PLK4-STIL Complex Assembly in Centriole Biogenesis
Zitouni, Sihem; Francia, Maria E.; Leal, Filipe; Montenegro Gouveia, Susana; Nabais, Catarina; Duarte, Paulo; Gilberto, Samuel; Brito, DanielaCentrioles are essential for the assembly of both centrosomes and cilia. Centriole biogenesis occurs once and only once per cell cycle and is temporally coordinated with cell-cycle progression, ensuring the formation of the right number of centrioles at the right time. The formation of new daughter centrioles is guided by a pre-existing, mother centriole. The proximity between mother and daughter centrioles was...
Regulation of Autophosphorylation Controls PLK4 Self-Destruction and Centriole ...
Cunha-Ferreira, Inês; Bento, Inês; Pimenta-Marques, Ana; Jana, Swadhin Chandra; Lince-Faria, Mariana; Duarte, Paulo; Borrego-Pinto, JoanaPolo-like kinase 4 (PLK4) is a major player in centriole biogenesis: in its absence centrioles fail to form, while in excess leads to centriole amplification. The SCF-Slimb/βTrCP-E3 ubiquitin ligase controls PLK4 levels through recognition of a conserved phosphodegron. SCF-Slimb/βTrCP substrate binding and targeting for degradation is normally regulated by phosphorylation cascades, controlling complex processes...