Introduction: Kawasaki disease (KD) is one of the most common vasculitides in childhood and may cause serious complications, namely coronary artery aneurism (CAA). KD may initially present with fever and otorhinolaryngological manifestations only, which may be misdiagnosed as deep neck infections. Case report: A four-year-old female was admitted for complicated acute tonsillitis. Cervical computed tomography su...
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Introduction: The axial articular involvement in pediatric inflammatory bowel disease is frequent and often asymptomatic. There are no studies evaluating the sacroiliac joints assessed by magnetic resonance colonography or enterography performed in this population. Methods: A cross-sectional study, including pediatric patients diagnosed with inflammatory bowel disease, previously submitted to magnetic resonance...
Introdução: A parotidite recorrente juvenil (PRJ) é uma inflaamação recidivante idiopática da glândula parótida, geralmente associada a sialectasia não-obstrutiva. A síndrome de Sjögren (SS), rara em idade pediátrica, pode apresentar-se nesta faixa etária sob a forma de parotidites de repetição. Caso clínico: Menina, de 13 anos, que no quarto episódio de tumefação e dor parotídea, iniciou investigação etiológic...
Introduction: To provide evidence-based guidance for the rati onal and safe prescripti on of biological therapies in children and adolescents with juvenile idiopathic arthriti s (JIAs), considering the latest available evidence and the new licensed biologics. Methods: Rheumatologists and Pediatricians with experti se in Pediatric Rheumatology updated the recommendati ons endorsed by the Portuguese Society of Rh...
Methods. We prospectively collected patient and disease characteristics from patients with JIA who started biological therapy. Adverse events were collected during the follow-up period. Predictors of response at 1 year and drug retention rates were assessed at 4 years of treatment for the first biologic agent.Results. A total of 812 JIA patients [65% females, mean age at JIA onset 6.9 years (s.d. 4.7)], 227 rec...
Introduction: This study aimed to assess the genetic determinants of poor outcome in Portuguese patients with juvenile idiopathic arthritis (JIA). Methods: Our study was conducted in Reuma.pt, the Rheumatic Diseases Portuguese Register, which includes patients with JIA. We collected prospectively patient and disease characteristics and a blood sample for DNA analysis. Poor prognosis was defined as CHAQ/HAQ >0.7...
Os autores apresentam um caso clínico de Artrite Idiopática Juvenil (A.LJ) - forma sistémica (Doença de Still), em criança do sexo feminino de 9 meses de idade, a propósito do qual fazem algumas considerações acerca do diagnostico, evolução clínica e terapêutica desta doença.
Os autores descrevem o caso clínico de uma criança do sexo feminino, de 2 anos e 9 meses de idade, que inicia em Julho/99, de forma insidiosa, dorso-lombalgia não acompanhada de sintomas constitucionais. Por persistência e agravamento progressivo das queixas álgicas, foi internada no Departamento de Pediatria do H. S. João em Setembro/99. Ao exame objectivo, evidenciava-se rigidez lombar acentuada, com mobiliza...