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Musculoskeletal manifestations of acute leukemia

Cordeiro, Catarina; Teixeira, Catarina; Jerónimo, Mónica; Silva, Sónia; Azevedo, Joana; Nascimento, João; Carvalho, Marcos; Tarquini, Oliana

Acute lymphoblastic leukemia (ALL) is the most common cause of malignancy in pediatric age. With the exception of musculoskeletal tumors, ALL is one of the malignancies most commonly associated with musculoskeletal symptoms at initial presentation. Some children with ALL are initially referred to Orthopedics for diagnostic evaluation, and a high index of clinical suspicion is required to avoid diagnostic delay....


Effectiveness of Intra-Arterial Chemotherapy for the Treatment of Intraocular R...

Castela, Guilherme; Providência, Joana; Monteiro, Madalena; Oliveiros, Bárbara; Silva, Sónia; Brito, Manuel; Machado, Egídio; Murta, Joaquim Neto

Purpose: We aim to report about effectiveness and safety in the context of our centers’ setting in the management of retinoblastoma with intra-arterial chemotherapy (IAC) in a 5-year retrospective analysis of the Portuguese population. Patients and Methods: Retrospective analysis of consecutive cases of retinoblastoma selected to initiate IAC between 2015 and 2020, at the Portuguese National Reference Center. A...


Characterization of the Portuguese population diagnosed with retinoblastoma

Castela, Guilherme; Providência, Joana; Monteiro, Madalena; Silva, Sonia; Brito, Manuel; Sá, Joaquim; Oliveiros, Bárbara; Murta, Joaquim Neto

The purpose of this study is to characterize demographically and genetically the Portuguese population with retinoblastoma; to report the clinical stage at presentation and its impact on survival and ocular preservation rate and, finally, to assess the incidence of retinoblastoma in Portugal. Retrospective observational study including children consecutively diagnosed with retinoblastoma at the Portuguese Natio...


Instrumental methods as strategic supporting tools for systematic biochemical a...

Oliveira, Jorge; Lemos, Carlota; Brito, Manuel; Pinto, António; Coutinho, Rui Coutinho; Barracosa, Paulo; Coelho, Catarina; Dinis, Rui

Serra da Estrela sheep crude milk is mandatory for the PDO Serra da Estrela (SE) cheese production. The production system implies the need for systematic knowledge of the values of useful matter (fat and protein) to produce cheese. The knowledge of somatic cell count (SCC) allows to predict the mammary health status of ewes as well as make decisions on the use of crude milk for human consumption, through its tr...


Quantitative analysis of hospitality and rural tourism supply and demand in Vis...

Pato, Maria Lúcia; Lemos, Carlota; Brito, Manuel

At a time that calls for tourism diversication and integrated accommodation, this work aimed to perform a quantitative analysis of tourism enterprises, particularly in Hotels and similar establishments and Rural Tourism. The analysis focused on Viseu Dão Lafões Region, an inland region that has sought to assert itself in terms of tourism, revealing a growth in tourist activity compared to the remaining Centro R...


Treatment of Advanced Retinoblastoma in Children Evacuated from Low-Income Coun...

Castela, Guilherme; Providência, Joana; Monteiro, Madalena; Silva, Sónia; Brito, Manuel; Murta, Joaquim Neto; Correa, Zélia; Castelo-Branco, Miguel

Objective: The aim of our study was to characterize the evacuated African patients diagnosed with retinoblastoma and referred to the Portuguese national referral center (Centro Hospital e Universitário de Coimbra, University of Coimbra), identifying inequalities in the stage of diagnosis and prognostic results. Design: Retrospective observational study of evacuated African patients diagnosed with retinoblastoma...


Análise quantitativa da oferta e procura na hotelaria e turismo rural na Região...

Pato, Maria Lúcia; Lemos, Carlota; Brito, Manuel

Numa altura em que se apela à diversificação crescente do turismo e procura de alojamentos integrados nos locais de destino, este trabalho procura compilar uma análise quantitativa da oferta de empreendimentos turísticos, em particular da Hotelaria e Turismo no Espaço Rural. A análise centra-se na Região Viseu Dão Lafões, uma região interior que tem procurado afirmar-se em termos turísticos, revelando um cresci...


GIS-Based clustering for characterization and implantation of vineyards in regi...

Brito, Manuel; Lemos, Carlota

Introduction: In 1989, the Távora-Varosa region was awarded the Denomination of origin, the first national wine-growing region demarcated for the production of sparkling wines. The morphological characteristics allow to create fresh wines with good acidity. Thus, it was intended to characterize and map the region in terms of elevation, slope, aspect and vineyard implantation. Material & Methods: For the delimit...


International Conference on Tourism and Social Support Technologies

Santos, Fernando Miguel Soares Mamede dos; Café, Afonso Pedro Ribeiro; Carvalho, Ana Branca; Guedes, Anabela; Pereira, Andreia; Oliveira, Ângela


Spatial and statistical analysis of tourism indicators – contribution to touris...

Lemos, Carlota; Brito, Manuel

Introduction: Considering the importance of tourism in the region of Viseu Dão Lafões which is differentiated by cultural values, thermal resources and wine-growing heritage, technologies of spatial and statistical analysis are essential for strategic planning in tourism in the region. Objectives: Analyze and map the tourism supply and demand, by municipality, regarding annual tourism indicators, with integrati...


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