2 documents found, page 1 of 1
G6PD deficiency in Latin America : systematic review on prevalence and variants
Monteiro, Wuelton Marcelo; Val, Fernando Fonseca de Almeida; Siqueira, André Machado; Franca, Gabriel Peixoto; Sampaio, Vanderson de SouzaPlasmodium vivax radical cure requires the use of primaquine (PQ), a drug that induces haemolysis in glucose-6-phosphate dehydrogenase deficient (G6PDd) individuals, which further hampers malaria control efforts. The aim of this work was to study the G6PDd prevalence and variants in Latin America (LA) and the Caribbean region. A systematic search of the published literature was undertaken in August 2013. Biblio...
Clinical complications of G6PD deficiency in Latin American and Caribbean popul...
Monteiro, Wuelton Marcelo; Franca, Gabriel Peixoto; Melo, Gisely Cardoso de; Queiroz, Amanda de Lourdes Maciel; Brito, Marcelo; Peixoto, Henry MaiaBackground: Although G6PDd individuals are generally asymptomatic throughout their life, the clinical burden of this genetic condition includes a range of haematological conditions, including acute haemolytic anaemia (AHA), neonatal jaundice (NNJ) and chronic non-sphaerocytic anaemia (CNSA). In Latin America (LA), the huge knowledge gap regarding G6PDd is related to the scarce understanding of the burden of cli...