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European contribution to the study of ROS: A summary of the findings and prospe...

Egea, Javier; Fabregat, Isabel; Frapart, Yves M; Ghezzi, Pietro; Görlach, Agnes; Kietzmann, Thomas; Kubaichuk, Kateryna; Knaus, Ulla G.

The European Cooperation in Science and Technology (COST) provides an ideal framework to establish multi-disciplinary research networks. COST Action BM1203 (EU-ROS) represents a consortium of researchers from different disciplines who are dedicated to providing new insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregu...


Resveratrol inhibits the mTOR mitogenic signaling evoked by oxidized LDL in smo...

Brito, Paula M.; Devillard, Raphaël; Nègre-Salvayre, Anne; Almeida, Leonor M.; Dinis, Teresa C. P.; Salvayre, Robert; Augé, Nathalie

http://www.sciencedirect.com/science/article/B6T12-4V0MTG8-1/2/7b7f3913eea3a6f05047e8c1927696a9


Resveratrol affords protection against peroxynitrite-mediated endothelial cell ...

Brito, Paula M.; Mariano, Anabela; Almeida, Leonor M.; Dinis, Teresa C. P.

Atherosclerosis, the main cause of cardiovascular disease (CD), is a chronic inflammatory condition associated with an overproduction of oxidant species, namely peroxynitrite, which is a powerful oxidant that reacts directly with all biomolecules. Glutathione is an efficient scavenger of peroxynitrite, so, modulation of glutathione synthesis may provide a strategy to selectively protect cells from this oxidant....


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