Background: Migraine is the most common neurological disorder and the second leading cause of disability. While the impact of migraine on daily life is often assessed by the frequency and intensity of attacks, the impairment between episodes is frequently overlooked. The four-item Migraine Interictal Burden Scale (MIBS-4) is a tool that can provide information and help in the evaluation of interictal disability...
Migraine is a cyclic condition with attacks consisting mainly of intense headaches, sensory intolerance, and nausea or vomiting. Loss of consciousness during attacks is often attributed exclusively to a neurally mediated reflex to pain, although it may also be due to migraine’s autonomic impairment, with cardiac conduction abnormalities, probably in relation to a degree of reduced sympathetic function. We repor...
Introduction: Hypnic headache is a rare headache disorder that requires strictly sleep-related attacks. There is also an ill-defined group of patients with recurrent predominant sleep-related nocturnal headache with occasional awake attacks, that are excluded from that diagnosis. Our aim was to compare these different groups and to understand whether their differences justify a distinct diagnosis. Methods: This...
Introduction: Migraine is the first cause of disability under 50 years of age. In the last decade there were significant advances in the comprehension of this disorder that led to the development of specific treatments, such as those targeting calcitonin gene-related peptide (CGRP) or its receptor including monoclonal antibodies. Here, we present real life results of a cohort of migraine patients treated with f...
Valério, D et al., Knowing how to do it or doing it? A double dissociation between tool-gesture production and tool-gesture knowledge, Cortex, https://doi.org/10.1016/j.cortex.2021.05.008; Deciding how to manipulate an object to fulfill a goal requires accessing different types of object-related information. How these different types of information are integrated and represented in the brain is still an open qu...
Introduction: In Portugal, new medical graduates undertake every year the Exame Nacional de Seriação, to be ranked for the available postgraduate residency posts within the National Health Service. Exame Nacional de Seriação is a multiple choice questions test on internal medicine.Objectives: This study analyses the Exame Nacional de Seriação results between 2006 and 2011, to identify the variables that predict...