7 documents found, page 1 of 1
A reação de Diels-Alder no início do século vinte um
Brocksom,Timothy John; Donatoni,Maria Carolina; Uliana,Marciana Pierina; Vieira,Ygor WilliamThe Diels-Alder reaction continues to be the premier method for the construction of complex organic molecules. In the last 10 years many developments have been introduced, and have led to increased utility of this reaction. In this review we present some of these novelties, which are of fundamental importance in organic synthesis.
A síntese dos sesquiterpenos baquenolidas
Brocksom,Timothy John; Brocksom,Ursula; Constantino,Maurício G.The bakkenolide group of sesquiterpenes has been a focal point of synthetic efforts amongst several research laboratories all linked to our common origins at the Chemistry Institute at the State University in São Paulo. In this review we would like to present a historical perspective of this research, with unpublished background information, and a definitive retrosynthetic analysis of these molecules. This chem...
A concise synthesis of the 1,6-disubstituted eudesmane sesquiterpene carbon ske...
Vieira,Ygor Willian; Nakamura,Joanita; Finelli,Fernanda Gadini; Brocksom,Ursula; Brocksom,Timothy JohnWe report a synthesis of the 1,6-disubstituted eudesmane sesquiterpene carbon skeleton, based upon a multicomponent Diels-Alder reaction.
O programa NAS/CNPq: avaliação de um participante
Brocksom,Timothy JohnThe NAS/CNPq programme in Chemistry ran from 1969 to 1974, and brought recent PhD and post-doctoral chemists to the Chemistry Institutes at the University of São Paulo and the Federal University of Rio de Janeiro. The purpose was to create and direct new research topics in selected areas of chemistry, and participate in the post-graduate programmes. As a participant in this programme, I present my personal view...
A reação de metátese de olefinas: reorganização e ciclização de compostos orgân...
Frederico,Daniel; Brocksom,Ursula; Brocksom,Timothy JohnThe olefin metathesis reaction allows the exchange of complex alkyl units between two olefins, with the formation of a new olefinic link and a sub-product olefin usually ethylene. This reaction has found extensive application in the last ten years with the development of the Grubbs and Schrock catalysts, in total synthesis of complex organic molecules, as opposed to the very important use in the petrochemical i...
The Diels-Alder reaction: an update
Brocksom,Timothy John; Nakamura,Joanita; Ferreira,Maria Lúcia; Brocksom,UrsulaThe last ten years have seen an explosive growth in synthetic applications of the Diels-Alder reaction, principally the intramolecular (IMDA) reaction but also the transannular (TADA) version. In this review we present these developments with special emphasis on the synthetic concepts and the experimental results and include related theoretical studies.
A evolução da pós-graduação em química no Brasil
Brocksom,Timothy John; Andrade,Jailson Bittencourt deThe post-graduate teaching of chemistry in Brazil over the last years is discussed, including comparisons with some other sciences and also experiences in the United States and the United Kingdom. We have also compared the more recent situation with the previous decade, which leads us to a favourable conclusion as to the results obtained in the teaching of post-graduate students in chemistry. Some conclusions a...