4 documents found, page 1 of 1
Did psychosocial status, sociodemographics and smoking status affect non-attend...
Malmqvist, Jessica; Siersma, Volkert; Thorsen, Hanne; Heleno, Bruno; Rasmussen, Jakob Fraes; Brodersen, John© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.; OBJECTIVES: We investigated if psychosocial status, sociodemographics and smoking status affected non-attendance in the control group in the randomised Danish Lung Cancer Screening Trial (DLCST). DESIGN AND SETTING: This study was an observational study nested in the DLC...
Overdiagnosis of lung cancer with low-dose computed tomography screening
Brodersen, John; Voss, Theis; Martiny, Frederik; Siersma, Volkert; Barratt, Alexandra; Heleno, BrunoIn low-dose computed tomography (LDCT) screening for lung cancer, all three main conditions for overdiagnosis in cancer screening are present: 1) a reservoir of slowly or nongrowing lung cancer exists; 2) LDCT is a high-resolution imaging technology with the potential to identify this reservoir; and 3) eligible screening participants have a high risk of dying from causes other than lung cancer. The degree of ov...
Quaternary prevention
Martins, Carlos; Godycki-Cwirko, Maciek; Heleno, Bruno; Brodersen, JohnPublisher Copyright: © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.; Background: According to the Wonca International Dictionary for General/Family Practice Quaternary Prevention is defined as: ‘Action taken to identify patient at risk of overmedicalization, to protect him from new medical invasion, and to suggest to him interventions, which are ethically acceptable.’ ...
Quantification of harms in cancer screening trials: literature review
Heleno, Bruno; Thomsen, Maria F; Rodrigues, David S; Jorgensen, Karsten J; Brodersen, JohnObjectives To assess how often harm is quantified in randomised trials of cancer screening. Design Two authors independently extracted data on harms from randomised cancer screening trials. Binary outcomes were described as proportions and continuous outcomes with medians and interquartile ranges. Data sources For cancer screening previously assessed in a Cochrane review, we identified trials from their referen...