<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background and Aims</jats:title> <jats:p>Enhanced levels of soluble tumor necrosis factor receptor 2 (sTNFR2) are known to associate with progressive chronic kidney disease (CKD), and is pointed as a potential biomarker for early detection of CKD; moreover, it has been reported as an independent predictor of all-cause mortality in end-stage renal disease ...
Long interspersed nuclear elements (LINE-1 or L1) are the most abundant retrotransposable elements accounting for nearly 17% of the human genome. These elements can be randomly incorporated in the genome, therefore having an important role in its plasticity and in generating structural genetic variants. It has been demonstrated that L1 retrotransposon activity may occasionally cause genetic diseases. To date, o...