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Polysaccharide-Based Carriers for Pulmonary Insulin Delivery: The Potential of ...

Valente, Sara A.; Lopes, Guido R.; Ferreira, Isabel; Galrinho, Miguel F.; Almeida, Margarida; Ferreira, Paula; Cruz, Maria T.; Coimbra, Manuel A.

Non-invasive routes for insulin delivery are emerging as alternatives to currently painful subcutaneous injections. For pulmonary delivery, formulations may be in powdered particle form, using carriers such as polysaccharides to stabilise the active principle. Roasted coffee beans and spent coffee grounds (SCG) are rich in polysaccharides, namely galactomannans and arabinogalactans. In this work, the polysaccha...


Brassica oleracea Var italica by-Products Prevent Lipid Accumulation and Cell D...

Castelão-Baptista, José P.; Valente, Sara A.; Canário, Sara; Oppolzer, David; Barros, Ana; Venâncio, Carlos; Martins, Tânia; Antunes, Luís

Obesity, a rising concern in the Eastern world, encompasses several co-morbidities, namely non-alcoholic fatty liver disease (NAFLD). Potential natural-based interventions to decrease the burden of obesity complications are being investigated. Many of the edible parts of plants are not sold for consumption and end up as massive waste, losing nutritional potential. In fact, a sizeable amount of waste is generate...


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