3 documents found, page 1 of 1
Subjective sleep parameters in prodromal Alzheimer’s disease: a case-control study
Borges,Conrado R.; Piovezan,Ronaldo D.; Poyares,Dalva R.; Busatto Filho,Geraldo; Studart-Neto,Adalberto; Coutinho,Artur M.; Tufik,SergioObjective: People with Alzheimer’s disease (AD) dementia have impaired sleep. However, the characteristics of sleep in the early stages of AD are not well known, and studies with the aid of biomarkers are lacking. We assessed the subjective sleep characteristics of non-demented older adults and compared their amyloid profiles. Methods: We enrolled 30 participants aged ≥ 60 years, with no dementia or major clini...
Topography of 11C-Pittsburgh compound B uptake in Alzheimer’s disease: a voxel-...
Faria,Daniele de P.; Duran,Fabio L.; Squarzoni,Paula; Coutinho,Artur M.; Garcez,Alexandre T.; Santos,Pedro P.; Brucki,Sonia M.; de Oliveira,Maira O.Objective: To compare results of positron emission tomography (PET) with carbon-11-labeled Pittsburgh compound B (11C-PIB) obtained with cerebellar or global brain uptake for voxel intensity normalization, describe the cortical sites with highest tracer uptake in subjects with mild Alzheimer’s disease (AD), and explore possible group differences in 11C-PIB binding to white matter. Methods: 11C-PIB PET scans wer...
A longitudial study of a neuropsychological rehabilitation program in Alzheimer...
Abrisqueta-Gomez,Jacqueline; Canali,Fabiola; Vieira,Vera L.D.; Aguiar,Ana Cristina P.; Ponce,Carmen S.C.; Brucki,Sonia M.; Bueno,Orlando F.A.Our aim was to study the duration of benefits derived from a neuropsychological rehabilitation program (NRP) for dementia patients. METHOD: The participants in this study were three patients diagnosed as probable Alzheimer's disease in the initial-to-moderate phase; the three were taking anticholinesterases. They were submitted to a neuropsychological evaluation (NE) before the NRP and then revaluated after 12 ...