8 documents found, page 1 of 1
“It’s a breech, and what now?”: A decision-aid tool to help clinicians counsel ...
Pinto, Luisa; Ayres-de-Campos, Diogo; Barbosa, MiguelObjective: Management options for breech presentation near term include vaginal breech delivery, cesarean delivery, and external cephalic version. Shared decision-making in this context involves conveying detailed information about each procedure, including success rates, potential discomforts, risks, recovery periods, and necessary follow-up. The complexity of this information can make discussions challenging....
Utilização de morcegos no controlo de pragas nas culturas
Marques, Paulo; Pulido-Valente, Sara; Mendes, Amarildo; Pinto, Luisa; Patanita, Maria IsabelA intensificação da agricultura, a alteração das práticas e o abandono das terras conduziram ao desaparecimento de algumas actividades agrícolas tradicionais que, ao longo do tempo, foram modelando a paisagem e propiciando a manutenção de condições favoráveis à presença de valores naturais e da biodiversidade que hoje estão protegidos por lei. A EDIA e o IPBeja propõem-se desenvolver ações que permitam sensibil...
Atitudes e Comportamentos Sexuais na Adolescência: Um Estudo Pioneiro em Portug...
Pinto, Luisa; Reis, MartaIntrodução: A vivência da sexualidade na adolescência está frequentemente associada ao início da atividade sexual, condicionando elevadas taxas de gravidez, de infeções sexualmente transmissíveis e de consequências psicológicas nefastas, com implicações pessoais, familiares e sociais marcantes. Esta é uma questão prioritária no âmbito da saúde pública. Este trabalho pretendeu avaliar atitudes e comportamentos s...
Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens ...
Cunha, Catarina Soares; Coimbra, Bárbara Guimarães Salazar; Pereira, Ana David; Borges, Sónia Maria de Sousa; Costa, Patrício Soares; Sousa, NunoStriatal dopamine receptor D1-expressing neurons have been classically associated with positive reinforcement and reward, whereas D2 neurons are associated with negative reinforcement and aversion. Here we demonstrate that the pattern of activation of D1 and D2 neurons in the nucleus accumbens (NAc) predicts motivational drive, and that optogenetic activation of either neuronal population enhances motivation in...
Glial plasticity in depression
Oliveira, João F.; Gomes, Catarina A.; Vaz, Sandra H.; Sousa, Nuno; Pinto, LuisaDepression is a highly prevalent disorder that poses a significant social burden to society. Despite continued advances toward the understanding of the pathophysiology of this disease, its molecular/cellular underpinnings remain elusive, which may be at the basis of the lack of effective treatment strategies. Among the different lines of research, recent literature suggests that impaired neuron and glial plasti...
The sweet drive test : refining phenotypic characterization of anhedonic behavi...
Pinheiro, António Mateus; Patrício, P.; Alves, N. D.; Santos, Ana R. Machado; Morais, Mónica; Bessa, J. M.; Sousa, Nuno; Pinto, LuisaMeasuring anhedonic behavior in rodents is a challenging task as current methods display only moderate sensitivity to detect anhedonic phenotype and, consequently, results from different labs are frequently incongruent. Herein we present a newly-developed test, the Sweet Drive Test (SDT), which integrates food preference measurement in a non-aversive environment, with ultrasonic vocalizations (USVs) recording. ...
Astrocyte pathology in the prefrontal cortex impairs the cognitive function of ...
Lima, A.; Sardinha, Vanessa Morais; Oliveira, A. F.; Reis, M.; Mota, Cristina de Fátima Sousa da; Silva, M. A.; Marques, Fernanda; Cerqueira, JoãoInterest in astroglial cells is rising due to recent findings supporting dynamic neuron-astrocyte interactions. There is increasing evidence of astrocytic dysfunction in several brain disorders such as depression, schizophrenia or bipolar disorder; importantly these pathologies are characterized by the involvement of the prefrontal cortex and by significant cognitive impairments. Here, to model astrocyte pathol...
The effects of chronic stress on hippocampal adult neurogenesis and dendritic p...
Bessa, J. M.; Pinto, Luisa; Morais, Mónica; Sousa, Nuno; Patrício, P.; Pinheiro, António Mateus; Almeida, Susana; Filipe, Augusto; Pedroso, PedroThere is accumulating evidence that adult neurogenesis and dendritic plasticity in the hippocampus are neuroplastic phenomena, highly sensitive to the effects of chronic stress and treatment with most classes of antidepressant drugs, being involved in the onset and recovery from depression. However, the effects of antidepressants that act through the selective inhibition of monoamine oxidase subtype A (MAO-A) i...