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International mobility flows and COVID-19 effects: evidence from Instituto Poli...
Lopes, Isabel Maria; Pais, Luís S.; Fernandes, Paula OdeteFacing the difficulties and the new challenges that COVID-19 has created for Higher Education Institutions (HEIs), the future needs to analyse and reflect on this crisis. Considering the increasing value of international mobility in Portuguese HEIs in the last decades, this research aims to study the effect of the COVID-19 pandemic on the flow of student and faculty mobility. Since international students, as we...
Separation of nadolol racemates by high pH reversed-phase fixed-bed and simulat...
Arafah, Rami; Ribeiro, António E.; Rodrigues, Alírio; Pais, Luís S.The separation of nadolol racemates under high pH reversed-phase using both the fixed-bed (FB) and the simulated moving bed (SMB) preparative chromatographic techniques is reported after the previous published work [1] where the Waters XBridge C18 adsorbent and an ethanol:water:diethylamine solvent mixture were validated to allow the separation of the multicomponent feed mixture composed by four nadolol stereoi...
Fixed-bed and simulated moving bed chromatography using achiral and chiral adso...
Arafah, Rami; Ribeiro, António E.; Rodrigues, Alírio; Pais, Luís S.Nadolol is a nonselective beta-adrenergic receptor antagonist (beta-blocker) pharmaceutical drug, widely used in the treatment of cardiovascular diseases, such as hypertension, ischemic heart disease (angina pectoris), congestive heart failure and certain arrhythmias. This drug is still being marketed as a mixture of four stereoisomers in spite of the clear evidences that only one of its four stereoisomers has ...
Fixed-bed and simulated moving bed chromatography using achiral and chiral adso...
Arafah, Rami; Ribeiro, António E.; Rodrigues, Alírio; Pais, Luís S.Nadolol is a nonselective beta-adrenergic receptor antagonist (beta-blocker) pharmaceutical drug, widely used in the treatment of cardiovascular diseases, such as hypertension, ischemic heart disease (angina pectoris), congestive heart failure and certain arrhythmias. This drug is still being marketed as a mixture of four stereoisomers in spite of the clear evidences that only one of its four stereoisomers has ...
Complete separation of the quaternary mixture of nadolol stereoisomers using pr...
Arafah, Rami; Ribeiro, António E.; Rodrigues, Alírio; Pais, Luís S.The separation and purification of high added value products by liquid chromatography is a very popular technique. The development of more stable and efficient stationary phases, together with the design of innovative and more flexible separation processes, enhanced the use of chromatographic processes, particularly at preparative and industrial scales through fixedbed and simulated moving bed (SMB) technologie...
Complete separation of the quaternary mixture of nadolol stereoisomers using pr...
Arafah, Rami; Ribeiro, António E.; Rodrigues, Alírio; Pais, Luís S.The separation and purification of high added value products by liquid chromatography is a very popular technique. The development of more stable and efficient stationary phases, together with the design of innovative and more flexible separation processes, enhanced the use of chromatographic processes, particularly at preparative and industrial scales through fixedbed and simulated moving bed (SMB) technologie...
Separation of nadolol racemates by high pH reversed-phase preparative chromatog...
Arafah, Rami; Ribeiro, António E.; Rodrigues, Alírio; Pais, Luís S.The separation of nadolol racemates under high pH reversed-phase preparative chromatography is presented for the first time. Three Waters C18 adsorbents (XBridge, Shield and XSelect) are compared for the separation of nadolol racemates using ethanol:water:diethylamine solvent mixtures. Experimental and simulation results are presented to compare the separation performances at preparative scale using both the fi...
Separation of nadolol racemates by high pH reversed-phase fixed-bed and simulat...
Arafah, Rami; Ribeiro, António E.; Rodrigues, Alírio; Pais, Luís S.Nadolol is a pharmaceutical chiral drug worldwide prescribed to the relief of some diseases mainly related with the cardiovascular system. Although some studies refer that the therapeutic effect of this drug is related with only one enantiomer, nadolol is still being marketed as a mixture of four stereoisomers, in a form of a racemic mixture of two racemates. The separation of all the four stereoisomers, despit...
O contributo do Instituto Politécnico de Bragança para a mão-de-obra qualificada
Paulo, Helena; Fernandes, Paula Odete; Pais, Luís S.Abrangendo os diferentes sectores empregadores da região Norte de Portugal, nomeadamente na NUT III de Alto Tâmega, Tâmega e Sousa, Terras de Trás-os-Montes e Douro e centrando-se, em especial, na formação superior conferida pelo Instituto Politécnico de Bragança, a presente investigação pretendeu conhecer, os meios e práticas de recrutamento e seleção de diplomados, e respetivas competências transversais recon...
O Ensino Superior e empregabilidade no mercado de trabalho
Paulo, Helena; Fernandes, Paula Odete; Pais, Luís S.Abrangendo os diferentes sectores empregadores da região Norte de Portugal, nomeadamente na NUT III de Alto Tâmega, Tâmega e Sousa, Terras de Trás-os-Montes e Douro e centrando-se, em especial, na formação superior conferida pelo Instituto Politécnico de Bragança, a presente investigação pretendeu conhecer, os meios e práticas de recrutamento e seleção de diplomados, e respetivas competências transversais recon...