2 documents found, page 1 of 1
Characterization and bioactivity of copaiba essential oil carried in a self-nan...
Ames-Sibin, Ana Paula; Chagas, Any C.; Ferreira, Sabrina B.S.; Mandim, Filipa; Finimundy, Tiane C.; Calhelha, Ricardo C.; Peralta, Rosane M.Copaiba essential oil (CEO) is the volatile part of copaiba balsam, which has been topically used for various inflammatory conditions. However, there are some concerns about the CEO safety for oral use. The lipophilic character of CEO also limits its application in the pharmaceutical field. This study prepared a selfnanoemulsifying drug delivery system (SNEDDS) containing CEO and evaluated its toxic effects aga...
Thermo- and pH-Responsive Gelatin/Polyphenolic Tannin/Graphene Oxide Hydrogels ...
Oliveira, Ariel C. de; Souza, Paulo R.; Vilsinski, Bruno H.; Winkler, Manuel E. G.; Bruschi, Marcos L.; Radovanovic, Eduardo; Muniz, Edvani C.Gelatin (GE), amino-functionalized polyphenolic tannin derivative (TN), and graphene oxide (GO) were associated to yield thermo- and pH-responsive hydrogels for the first time. Durable hydrogel assemblies for drug delivery purposes were developed using the photosensitizer methylene blue (MB) as a drug model. The cooling GE/TN blends provide brittle physical assemblies. To overcome this disadvantage, different G...