4 documents found, page 1 of 1
Hyperthermic Intrathoracic Chemotherapy. A new weapon has been deployed in Port...
Barata, Catarina; Ferreira, Ricardo; Draiblate, Beatriz; Pereira, Filipe; Brysch, Eva; Nobre, ÂngeloThymoma is a relatively rare tumour, being, nonetheless, the most frequent neoplasm of the anterior mediastinum. Radical surgery is the gold-standard in every stage, with a considerable recurrence rate in locally advanced tumours. Complete resection in recurrences occurs only in a few cases. A new therapeutic strategy has emerged: the Hyperthermic Intrathoracic Chemotherapy (HITHOC), a high concentrated dose of...
A Rare Presentation of Multi-Organ Embolism in a Multifactorial Hypercoagulable...
Brysch, Eva; Salgado, Sara; Santos, António Carvalheira; Bárbara, CristinaParadoxical embolism is an uncommon phenomenon, accounting for only 2% of all cases of systemic arterial embolism. This condition suggests the presence of a patent foramen ovale, present in 20% - 25% of the adult population. The authors report the case of a 63-year-old male patient with a history of lung adenocarcinoma and hereditary thrombophilia admitted to hospital with acute onset of dyspnea, diplopia, conf...
Detection and quantification of EGFR T790M mutation in liquid biopsies by dropl...
Silveira, Catarina; Sousa, Ana Carla; Janeiro, André; Malveiro, Sara; Teixeira, Encarnação; Brysch, Eva; Pantarotto, Marcos; Felizardo, MargaridaBackground: Liquid biopsy allows the identification of targetable cancer mutations in a minimally invasive manner. In patients with advanced non-small cell lung cancer (NSCLC), droplet digital PCR (ddPCR) is increasingly used to genotype the epidermal growth factor receptor (EGFR) gene in circulating cell-free DNA (cfDNA). However, the sensitivity of this method is still under debate. The aim of this study was ...
DEFINITIVE TREATMENT OF PRIMARY SPONTANEOUS PNEUMOTHORAX: A 10-YEAR EXPERIENCE
Brysch, Eva; Gonçalves, João; Ferreira, Ricardo; Sena, André; Freitas, Francisco; Monteiro, Paula; Nobre, Ângelo; Bárbara, CristinaObjectives: Primary spontaneous pneumothorax (PSP) is defined as a pneumothorax without obvious underlying lung disease. Definitive treatment should be offered to patients with recurrent or persistent PSP. The aim of this study was to compare the effectiveness of medical pleurodesis (MP) with video assisted thoracic surgery (VATS) on definitive treatment of PSP. Methods: 10 years’ retrospective study of PSP pat...