Tuberculosis (TB) is a transmissible disease listed as one of the 10 leading causes of death worldwide (10 million infected in 2019). A swift and precise diagnosis is essential to forestall its transmission, for which the discovery of effective diagnostic biomarkers is crucial. In this study, we aimed to discover molecular biomarkers for the early diagnosis of tuberculosis. Two independent cohorts comprising 29...
Enquadramento: Os cuidados às pessoas dependentes no autocuidado a viver no domicílio e a sua provisão são uma realidade complexa e multidimensional, não estando em muitas situações garantida a sua completude. São escassos os estudos que analisam as razões deste fenómeno. Objetivo: Conhecer as razões que, na perspetiva dos enfermeiros, subjazem à existência de cuidados que não são realizados ou que não são real...
IP Guarda
TP53 gene deletions or mutations were related to more aggressiveness in invasive and in situ bladder tumors. However, its prognostic value in the superficial ones is not well defined. Sixty-two cases with low-grade superficial urothelial cell carcinomas (uccs) were studied. twenty-two suffered recurrence and 10 of these progressed. FiSH for TP53 detection and immunohistochemistry for p53 with both Do7 and Ab-24...