2 documents found, page 1 of 1
Copper-64 Chloride Exhibits Therapeutic Potential in Three-Dimensional Cellular...
Pinto, Catarina I. G.; Bucar, Sara; Alves, Vítor H. P.; Fonseca, Alexandra; Abrunhosa, Antero J.; da Silva, Cláudia L.; Guerreiro, Joana F.Prostate cancer (PCa) is the second most common cancer type in men, and in advanced metastatic stages is considerable incurable. This justifies the need for efficient early diagnostic methods and novel therapies, particularly radiopharmaceuticals with the potential for simultaneous diagnosis and therapy (theranostics). We have previously demonstrated, using monolayer-cultured cells, that copper-64 chloride, a p...
Naive and stem cell memory T cell subset recovery reveals opposing reconstituti...
Soares, Maria Vieira; Azevedo, Rita I.; Ferreira, Ines; Bucar, Sara; Ribeiro, Ana C.; Vieira, Ana I. S.; Pereira, Paulo N G; Ribeiro, Ruy M.The success of allogeneic hematopoietic stem cell transplantation (allo-HSCT) in the treatment of hematological malignancies remains hampered by life-threatening chronic graft vs. host disease (cGVHD). Although multifactorial in nature, cGVHD has been associated with imbalances between effector and regulatory T cells (Treg). To further elucidate this issue, we performed a prospective analysis of patients underg...