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HLA‐A23/HLA‐A24 serotypes and dementia interaction in the elderly: Association ...

Cardoso, Elsa M.; Gomes, Vânia Lourenço; Esgalhado, André J.; Ferreira, Débora Reste; Oliveira, Nádia; Amaral, Ana Saraiva; Martinho, António

MHC class I molecules regulate brain development and plasticity in mice and HLA class I molecules are associated with brain disorders in humans. We investigated the relationship between plasma-derived soluble human HLA class I molecules (sHLA class I), HLA class I serotypes and dementia. A cohort of HLA class I serotyped elderly subjects with no dementia/predementia (NpD, n = 28), or with dementia (D, n = 28) w...

Date: 2023   |   Origin: uBibliorum
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