5 documents found, page 1 of 1
Phenolic acids-loaded thermosensitive hydrogel for intracanal biofilm management
Santos, Vanessa Rodrigues dos; Caiaffa, Karina Sampaio; Souza, Amanda Caselato Andolfato; Pereira, Jesse Augusto; Abuna, Gabriel FloresObjective: In search of an inter-appointment intracanal medication capable of promoting root canal disinfection while preserving the viability of periapical cells, this study synthesized and characterized chitosan-poloxamer hydrogels (CPH) containing phenolic acids and evaluated their effects on multispecies biofilms and cell viability for potential endodontic use. Methods: Cinnamic acid (CI), caffeic acid (CA)...
Cytocompatibility and Synergy of EGCG and Cationic Peptides Against Bacteria Re...
Caiaffa, Karina Sampaio [UNESP]; dos Santos, Vanessa Rodrigues [UNESP]; Abuna, Gabriel Flores; Santos-Filho, Norival Alves [UNESP]Made available in DSpace on 2022-04-29T08:31:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; This study evaluated the cytocompatibility and antimicrobial/antibiofilm effects of epigallocatechin-3-gallate (EGCG) associated with peptide LL-37 and its analogue KR-12-a5 against oral pathogens. The effect of the compounds on metabolism of fibroblasts was evaluated by methyltetrazolium assays. Antimi...
Cytotoxicity and effects of curcumin and cinnamaldehyde hybrids on biofilms of ...
Dos Santos, Vanessa Rodrigues [UNESP]; Caiaffa, Karina Sampaio [UNESP]; Oliveira, Warlley Campos de [UNESP]; Pereira, Jesse Augusto [UNESP]Made available in DSpace on 2022-04-29T08:30:32Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; The objective of the study was to evaluate the cytotoxicity and effect of curcumin-cinnamaldehyde hybrids (CCHs) on the biofilm of oral pathogens. Of the 18 hybrids tested, nine had an inhibitory effect on at least one of the bacterial species tested, with minimal inhibitory and bactericidal concentrati...
KR-12-a5 is a non-cytotoxic agent with potent antimicrobial effects against ora...
Caiaffa, Karina Sampaio [UNESP]; Massunari, Loiane [UNESP]; Danelon, Marcelle [UNESP]; Abuna, Gabriel Flores; Bedran, Telma Blanca Lombardo [UNESP]Made available in DSpace on 2018-12-11T17:15:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-11-26; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); This study evaluated the cytotoxicity and antimicrobial activity of analogs of cationic peptides against microorganisms associated with endodontic infections. L-929 fibroblasts were exposed to LL-37, KR-12-a5 and hBD-3–1CV and chlorhe...
Cytotoxicity and the effect of cationic peptide fragments against cariogenic ba...
Kreling, Paula Fernanda [UNESP]; Aida, Kelly Limi [UNESP]; Massunari, Loiane [UNESP]; Caiaffa, Karina Sampaio [UNESP]; Percinoto, Célio [UNESP]Made available in DSpace on 2018-12-11T17:06:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-08-18; This study evaluated the cytotoxicity and effect of fragments derived from three oral cationic peptides (CP): LL-37, D6-17 and D1-23 against cariogenic bacteria under planktonic and biofilm conditions. For cytotoxicity analysis, two epithelial cell lines were used. The minimum inhibitory concentration a...