5 documents found, page 1 of 1
Development of the PraziCalc mobile device-app to calculate praziquantel dosage...
Viana, Agostinho Gonçalves; Coelho, André Luiz Gomes; Gazzinelli-Guimarães, Pedro Henrique; Phillips, Anna E.; Bartholomeu, Daniella Castanheira
Regulatory monocytes in helminth infections: insights from the modulation durin...
Mendes, Tiago Antônio de Oliveira; Passos, Lívia Silva Araújo; Gazzinelli-Guimarães, Pedro Henrique; Guimarães, Ana Clara GazzinelliWhile the macrophage polarization is well characterized in helminth infections, the natural heterogeneity of monocytes with multiple cell phenotypes might influence the outcome of neglected diseases, such hookworm infection. Here, we report the profile of monocytes in human hookworm infections as a model to study the regulatory subpopulation of monocytes in helminth infections. Blood samples were collected from...
A new methodology for evaluation of nematode viability
Ferreira, Sebastião Rodrigo; Mendes, Tiago Antônio Oliveira; Bueno, Lilian Lacerda; Araújo, Jackson Victor de; Bartholomeu, Daniella CastanheiraNematodes infections are responsible for debilitating conditions and economic losses in domestic animals as well as livestock and are considered an important public health problem due to the high prevalence in humans. The nematode resistance for drugs has been reported for livestock, highlighting the importance for development of new anthelmintic compounds. The aim of the current study was to apply and compare ...
Immunodiagnosis of canine visceral leishmaniasis using mimotope peptides select...
Machado, Christina Monerat Toledo; Ávila, Ricardo Andrez Machado de; NGuyen, Christophe; Granier, Claude; Bueno, Lilian LacerdaELISA and RIFI are currently used for serodiagnosis of canine visceral leishmaniasis (CVL). The accuracy of these tests is controversial in endemic areas where canine infections by Trypanosoma cruzi may occur.We evaluated the usefulness of synthetic peptides that were selected through phage display technique in the serodiagnosis of CVL. Peptides were chosen based on their ability to bind to IgGs purified from i...
Antigenicity of a whole parasite vaccine as promising candidate against canine ...
Giunchetti, Rodolfo Cordeiro; Reis, Alexandre Barbosa; Lemos, Denise da Silveira; Martins Filho, Olindo Assis; Oliveira, Rodrigo Corrêa deHuman visceral leishmaniasis, one of the most important zoonoses, is caused by the protozoaLeishmania chagasi(syn. L. infantum ) and is present as a fatal disease common in South America and Europe where dogs and wild canids are the main reservoirs. A vaccine against visceral leishmaniasis would be an important tool in the control of this disease in dogs. Although the current strategies for vac-cination against...