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Adiponectin, Leptin, and IGF-1 are useful diagnostic and stratification biomark...

Marques, Vanda; Afonso, Marta; Bierig, Nina; Duarte-Ramos, Filipa; Santos-Laso, Álvaro; Jimenez-Agüero, Raul; Eizaguirre, Emma; Bujanda, Luis

Background: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease where liver biopsy remains the gold standard for diagnosis. Here we aimed to evaluate the role of circulating adiponectin, leptin, and insulin-like growth factor 1 (IGF-1) levels as non-invasive NAFLD biomarkers and assess their correlation with the metabolome. Materials and Methods: Leptin, adiponectin, and IGF-1 seru...


Preguntas y errores en el diagnóstico y manejo de la anemia en pacientes con he...

Mearin, Fermín; Lanas, Ángel; Bujanda, Luis; Canelles, Pilar; Cotter, José Almeida Berkeley; Hervás, Antonio; Argila, Carlos Martín de; Montoro, Miguel

Despite high prevalence of iron deficiency anemia (IDA) in patients with acute or chronic gastrointestinal bleeding (GIB), IDA and iron deficiency (ID) are frequently untreated. Reasons may be misconceptions about the impact and diagnosis of IDA and the efficacy of new treatments. Addressing these misconceptions, this article summarizes current evidence for better understanding and management of GIB-associated ...


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