2 documents found, page 1 of 1
Prognostic factors in patients with advanced differentiated thyroid cancer trea...
Treistman,Natalia; Nobre,Gabriela Maia; Tramontin,Mariana Yoshii; Silva,Gabriel Madeira Werberich da; Herchenhorn,Daniel; Araujo,Luiz Henrique de LimaABSTRACT Objective: The aim of this study was to describe the real-world experience multikinase inhibitors (MKI) in the treatment advanced differentiated thyroid carcinoma (DTC) refractory to radioactive iodine (RAIR) therapy. Subjects and methods: We reviewed the records of all patients with MKI-treated DTC from 2010 to 2018. Progression free survival (PFS), response rates (RR) and adverse events (AE) profiles...
Cholestatic syndrome as initial manifestation of pancreatic metastasis of papil...
Tramontin,Mariana Yoshii; Faria,Paulo Antônio Silvestre de; Nascimento,Cristina Moreira do; Barbosa,Cibele de Aquino; Barros,Maria de Fátima Rei PereiraSUMMARY Most papillary thyroid carcinomas (PTC) harbor excellent prognosis. Although rare, distant metastases normally occur in lungs and/or bones. Here we describe a rare case of pancreatic metastasis presenting with rapid onset cholestatic syndrome. A literature review was also performed. A 73-year-old man with a high risk PTC was submitted to total thyroidectomy (TT) followed by radioiodine therapy. After in...