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Organic effects of associating paclitaxel with a lipid-based nanoparticle syste...

Feio, Danielle Cristinne Azevedo; Oliveira, Nayara Cristina Lima de; Pereira, Edmundo Luis Rodrigues; Morikawa, Aleksandra Tiemi

Lipid-based nanoparticle systems have been used as vehicles for chemotherapeutic agents in experimental cancer treatments. Those systems have generally been credited with attenuating the severe toxicity of chemotherapeutic agents. This study aimed to investigate the effects of associating paclitaxel (PTX) with a lipid-based nanoparticle system on a nonhuman primate, Cebus apella, documenting the toxicity as mea...

Date: 2017   |   Origin: Oasisbr


Occurrence of Helicobacter pylori and Epstein-Barr virus infection in endoscopi...

Souza, Carolina Rosal Teixeira de; Oliveira, Kátia Soares de; Ferraz, Jefferson José Sodré; Leal, Mariana Ferreira; Calcagno, Danielle Queiroz

Background: Helicobacter pylori (HP) and Epstein-Barr virus (EBV) have been associated with cancer development. We evaluated the prevalence of HP, HP CagA+ and EBV infection in gastric cancer (GC) samples from adults and in gastric tissues from patients who underwent upper endoscopy (UE). Methods: Samples from UE and GC were collected to investigate the presence of HP infection and the HP virulence factor CagA ...

Date: 2014   |   Origin: Oasisbr

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