50 documents found, page 1 of 5

Exploring a novel approach to cybersecurity : the role of ecological simulation...

In response to the growing cybersecurity problem, this study presents an innovative approach using virtual reality to train individuals in reducing the risk of cyberattacks. The research involved 70 adult participants with or enrolled in higher education studies, who participated in a virtual reality task that simulates a typical workday in a corporate setting. The participants were divided into three groups: a...

Beyond the screen : exploring the player’s role and its impact on emotional exp...

This article explores the idea of the player as a co-creator of their own experience in video games, focusing on how we can define their role within the game’s architecture and how they shape their emotional experiences. By agreeing to an implicit ‘contract’ as they play a video game, players not only accept to adhere to the rules of the game world but allow themselves to become engaged in the game’s narratives...

An effective decision-making trilogy: data-driven, artificial intelligence, and...

This paper presents an insightful analysis of the trilogy of data-driven tech niques, artificial intelligence (AI), and blockchain technology as a power structure that contributes to an efficient, agile, and secure decision-making process based on the analysis of large datasets is further enhanced by the integration of more receptive AI techniques, enabling pattern recognition, prediction, and automation. Meanw...

MEERU Aproxima: relatório de avaliação

A Rare Case of Unilateral Tongue Edema with Angiotensin Converting Enzyme Inhib...

Angiotensin converting enzyme inhibitors (ACEi) are widely used for the treatment of multiple conditions such as hypertension, heart failure and chronic kidney disease. Angioedema is a rare but potentially fatal complication of ACEi use and unilateral tongue edema is a very rare presentation. We report a case of a 55-year-old man, with a history of hypertension, on enalapril for three years, who presented to th...

Hypoxia and Macrophages Act in Concert Towards a Beneficial Outcome in Colon Ca...

In colon cancer, the prognostic value of macrophages is controversial, and it is still unknown how hypoxia modulates macrophage-cancer cell crosstalk. To unravel this, co-cultures of human primary macrophages and colon cancer cells were performed at 20% and 1% O2, followed by characterization of both cellular components. Different colon cancer patient cohorts were analyzed for hypoxia and immune markers, and th...

Relative Abundance and Compositional Variation of Silicates, Oxides and Phospha...

Panasqueira is a world-class W-Sn-Cu lode-type deposit located in Portugal. It consists of a dense swarm of subhorizontal quartz lodes criss-crossed by several ENE–WSW and N–S fault zones, bordering Late Variscan granite and hosted in Late Ediacaran—Early Cambrian metasediments. The relative abundance and compositional variation (assessed with EPMA) of the main silicates, oxides and phosphates forming the quart...

The T-box transcription factor brachyury behaves as a tumor suppressor in gliomas

The oncogene brachyury (TBXT) is a T-box transcription factor that is overexpressed in multiple solid tumors and is associated with tumor aggressiveness and poor patient prognosis. Gliomas comprise the most common and aggressive group of brain tumors, and at the present time the functional and clinical impact of brachyury expression has not been investigated previously in these neoplasms. Brachyury expression (...

Brachyury Is associated with glioma differentiation and response to temozolomide

Glioblastomas (GBMs) are the most aggressive tumor type of the central nervous system, mainly due to their high invasiveness and innate resistance to radiotherapy and chemotherapy, with temozolomide (TMZ) being the current standard therapy. Recently, brachyury was described as a novel tumor suppressor gene in gliomas, and its loss was associated with increased gliomagenesis. Here, we aimed to explore the role o...

Qual o papel da educação para os direitos humanos?