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Molecular signatures of xenograft colorectal cancer in mice treated with topotecan

Hagyousif, Yousra A.; Zenati, Ruba A.; Soares, Nelson C.; Al-Hroub, Hamza M.; Khan, Farman Matloob; Qaisar, Rizwan; Hamoudi, Rifat; El-Awady, Raafat

Funding Information: The authors would like to acknowledge The University of Sharjah financial support. This study was financially supported by the University of Sharjah (competitive grant number 2201110155 and targeted grant number 24011101105 ). Publisher Copyright: © 2025 The Authors; Background: Colorectal cancer (CRC) is one of the most common cancers worldwide, yet it continues to have a low survival rate...


Global age-sex-specific all-cause mortality and life expectancy estimates for 2...

Schumacher, Austin E.; Zheng, Peng; Barber, Ryan M.; A, Bhoomadevi; Aalipour, Mohammad Amin; Aalruz, Hasan; Ababneh, Hazim S.; Abaraogu, Ukachukwu O.

Publisher Copyright: © 2025 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.; Comprehensive, comparable, and timely estimates of demographic metrics—including life expectancy and age-specific mortality—are essential for evaluating, understanding, and addressing trends in population health. The COVID-19 pandemic highlighted the importance of timely and all-cau...


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