3 documents found, page 1 of 1
Aloysia citrodora extract as a chemopreventive agent against HPV16-induced lesi...
Medeiros-Fonseca, Beatriz; Faustino-Rocha, Ana I.; Silva, Jéssica; Silva, Mónica G.; Pires, Maria João; Neuparth, Maria João; Vala, HelenaAim: Aloysia citrodora has a long history of traditional use in treating various ailments. This study evaluated the in vivo chemopreventive efficacy and systemic toxicity of an extract of A. citrodora in a transgenic mouse model of HPV16 (human papillomavirus type 16)-induced cancer. Methods: The experiment involved six groups (n = 5): group 1 (G1, wild-type (WT), water), group 2 (G2, HPV, water), group 3 (G3, ...
A One Health Perspective on Q Fever: Part 1
Cruz, Rita; C, Vasconcelos-Nóbrega; Esteves, Fernando; Coelho, Catarina; Ferreira, Ana Sofia; Santos, Carla; Mega, Cristina; Coelho, Ana C.Q fever is a worldwide zoonotic infectious disease caused by Coxiella burnetii and ruminants, namely, cattle, sheep, and goats, are known to be the main reservoir for human infection. C. burnetii infection in animals can result in epizootic abortions which are often associated with vast bacteria shedding in birth fluids and placentas. Human infections mainly occur in persons handling infected animals and their ...
A One Health Perspective on Q Fever: Part 2
Cruz, Rita; C, Vasconcelos-Nóbrega; Esteves, Fernando; Coelho, Catarina; Ferreira, Ana Sofia; Santos, Carla; Mega, Cristina; Coelho, Ana C.Q fever, a widespread zoonotic disease caused by Coxiella burnetiid, produces a complex and polymorphic disease in humans. As a zoonotic disease, control in animals will influence the level of disease seen in humans, thus resulting in interesting one health perspectives for disease control. Here the authors describe the clinical manifestations in animals and humans, as well as the current diagnostic methods ava...