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Pharmacotherapeutic follow-up of patients with Chagas disease using in use of b...
Correia, João Paulo Ramalho; Costa, Alanna Carla da; Rocha, Eduardo Arrais; Quidute, Ana Rosa Pinto; Cândido, Darlan da SilvaIntroduction : Benznidazole (BNZ) is a drug available for the etiological treatment of Chagas disease. However, this drug is toxic and has a limited effectiveness on the chronic phase of this disease, often leading to poor treatment adherence. Methods: This is a descriptive and exploratory study conducted at the Pharmaceutical Care Service for Chagas disease patients of the Federal University of Ceará. Drug-rel...
Clinical and serological evolution in chronic Chagas disease patients in a 4-ye...
Andrade, Mônica Coelho; Oliveira, Maria de Fátima; Nagao-Dias, Aparecida Tiemi; Coêlho, Ivo Castelo Branco; Bezerra, Fernando Schemelzer MoraesIntroduction: The role of trypanocidal therapy in the chronic phase of Chagas disease remains controversial. Methods: A total of 13 patients with chronic Chagas disease were treated with benznidazole (5mg/kg/day/60 days) and surveyed via antibody measurement and conventional electrocardiogram over the course of 4 years. Results: The antibody titers were signifi cantly reduced after 4 years (p<0.05). Most of the...