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IL-5 serum and appendicular lavage fluid concentrations correlate with eosinoph...

Carvalho, Nuno; Carolino, Elisabete; Coelho, Hélder; Cóias, Ana; Trindade, Madalena; Vaz, João; Cismasiu, Brigitta; Moita, Catarina; Moita, Luis

Appendicitis is the most common abdominal surgical emergency, but its aetiology is not fully understood. We and others have proposed that allergic responses play significant roles in its pathophysiology. Eosinophils and Interleukin (IL)-5 are involved in a hypersensitivity type I reaction. Eosinophil infiltration is common in the allergic target organ and is dependent on IL-5. In the presence of an allergic com...


HELICOBACTER PYLORI AND THE ATHEROGENIC PROCESS IN CARDIOVASCULAR DISEASE

Carvalho, Nuno; Cóias, Ana; Coelho, Hélder; Marcelino, Gisela; Albergaria, Diogo; Ferreira, Maria José; Brito, Maria José; Corte Real, João

Background: Conventional risk factors do not explain completely the atherogenic process. Chronic Helicobacter pylori (HP) infection may cause arterial inflammation and has been epidemiologically linked to the occurrence of atherosclerosis. Studies about the association of HP infection with peripheral arterial disease are limited. Objective: Evaluate the presence of HP using a monoclonal antibody anti-HP in the ...

Date: 2018   |   Origin: Angiologia e Cirurgia Vascular

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