2 documents found, page 1 of 1
Obesity impairs resistance to Leishmania major infection in C57BL/6 mice.
Martins, Vinicius Dantas; Campos, Franciele Carolina Silva; Moreira, Felipe Caixeta; Carneiro, Matheus Batista Heitor; Goes, Grazielle RibeiroAn association between increased susceptibility to infectious diseases and obesity has been described as a result of impaired immunity in obese individuals. It is not clear whether a similar linkage can be drawn between obesity and parasitic diseases. To evaluate the effect of obesity in the immune response to cutaneous Leishmania major infection, we studied the ability of C57BL/6 mice fed a hypercaloric diet (...
Splenectomy does not interfere with immune response to Leishmania major infecti...
Maioli, Tatiani Uceli; Carneiro, Cláudia Martins; Assis, Frankcinéia Aparecida de; Faria, Ana Maria Caetano deSpleen is one of the largest lymphoid organs in the body; it harbors immune cells including antigen presenting cells, B and T lymphocytes. It has an important role in humoral and cellular immune responses. Herein we investigated the role of spleen in the immune response to experimental Leishmania major infection. It is known that C57BL/6 mice are resistant to L. major infection whereas BALB/c mice are susceptib...