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Analysis of salivary levels of IL-1β, IL17A, OPG and RANK-L in periodontitis us...

Relvas, Marta; Silvestre, Ricardo Jorge Leal; Gonçalves, Maria; Cabral, Cristina; Frias, Ana Isabel Mendes; Monteiro, Luís; Viana da Costa, Alexandra

Periodontitis is a chronic disease with a high overall prevalence. It involves a complex interplay between the immune-inflammatory pathways and biofilm changes, leading to periodontal attachment loss. The aims of this study were (i) to assess whether the salivary IL-1β, IL-17A, RANK-L and OPG levels have the potential to discriminate between the mild and severe periodontitis conditions; and (ii) to enable diagn...



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