12 documents found, page 1 of 2
Large brown macula in a newborn
Santos Oliveira, Ana Gisela; Marques, João; Antunes, Joaquina; Maneira Sousa, Pedro; Cabral, Rita; Andrade, IsabelThe authors report the case of a male term newborn born after an uneventful monitored pregnancy. On physical examination, he presented with a light brown hyperpigmented homogeneous macule >15 cm in size compatible with a giant congenital melanocytic nevus (CMN). The boy was discharged with indication for Neonatology and Dermatology follow-up. Since then, he has shown adequate psychomotor growth and development ...
Contributo para a validação final da versão portuguesa do questionário Speech H...
Cabral, RitaObjetivos: Contribuir para a validação final da versão portuguesa do questionário Speech Handicap Index (SHI) em indivíduos com disartria após-Acidente Vascular Cerebral (AVC), analisar o impacto da disartria nos indivíduos através da auto-perceção das alterações da produção de fala e analisar a perceção global do impacto das alterações de fala do indivíduo com disartria pós-AVC comparativamente à perceção do t...
Combination of chemotherapy and Au-nanoparticle photothermy in the visible ligh...
Pedrosa, Pedro; Mendes, Rita; Cabral, Rita; Martins, Luisa; Baptista, Pedro; Fernandes, AlexandraDespite great advances in the fight against cancer, traditional chemotherapy has been hindered by the dose dependent adverse side effects that reduce the usable doses for effective therapy. This has been associated to drug resistance in tumor cells that often cause relapse and therapy failure. These drawbacks have been tackled by combining different therapeutic regiments that prevent drug resistance while decre...
MERKEL CELL CARCINOMA – REPORT OF 7 CASES
Cabral, Rita; Brinca, Ana; Vieira, Ricardo; Mariano, Angelina; Tellechea, Óscar; Figueiredo, AméricoIntroduction: Merkel cell carcinoma is a rare, aggressive cutaneous neuroendocrine carcinoma that affects primarily elderly people. Patients present with a rapidly growing nodule, preferably located at the head, neck and limbs. Merkel cell carcinoma as a propensity for local recurrence and regional lymph node metastases and wide local excision is the initial consensual approach. The role of lymph node dissectio...
ACTINIC CHEILITIS: CO2 LASER ABLATION VERSUS VERMILIONECTOMY – ELEVEN YEAR ANAL...
Cabral, Rita; Teixeira, Vera; Vieira, Ricardo; Figueiredo, AméricoBackground: Actinic cheilitis is a pre-malignant lesion affecting predominantly the vermilion of the inferior lip of male patients. Objectives: Our aim was compare two treatment options for Actinic cheilitis: ablation with CO2 laser and vermilionectomy. Methods: Retrospective study of patients with Actinic cheilitis treated with CO2 laser ablation or vermilionectomy, in an 11 year period.Results: 51 caucasian ...
NODULAR MALIGNANT MELANOMA - OR MAYBE NOT?
Cabral, Rita; Brinca, Ana; Cardoso, José Carlos; Tellechea, ÓscarEccrine poroma is a relatively rare benign adnexal tumor with multiple clinical presentations, mimicking several other cutaneous neoplasms. The pigmented form is uncommon and usually located in nonacral sites in non-white patients. The authors present the case of a patient with a pigmented tumoural lesion on the left shoulder clinically thought to represent nodular malignant melanoma, but whose histopathology r...
SENTINEL NODE BIOPSY IN PORTUGAL - THE EXPERIENCE OF A REFERENCE A CENTER
Teixeira, Vera; Vieira, Ricardo; Coutinho, Inês; Cabral, Rita; Andrade, Pedro; Julião, Maria José; Brites, Maria Manuel; Albuquerque, AnabelaBackground: Sentinel lymph node biopsy is undertaken as a standard procedure for patients with localized cutaneous melanoma. The National Comprehensive Cancer Network (NCCN) melanoma panel has reinforced the status of Sentinel lymph node biopsy as the most important prognostic factor for disease survival.Objectives: We sought to identify predictive factors associated with positive SLN biopsy and correlation wit...
Screening of copy number variants in the 22q11.2 region of congenital heart dis...
Pires, Renato; Pires, Luís M.; Vaz, Sara O.; Maciel, Paula; Anjos, Rui; Moniz, Raquel; Branco, Claudia C.; Cabral, Rita; Carreira, Isabel M.Background The rearrangements in the 22q11.2 chromosomal region, responsible for the 22q11.2 deletion and microduplication syndromes, are frequently associated with congenital heart disease (CHD). The present work aimed to identify the genetic basis of CHD in 87 patients from the São Miguel Island, Azores, through the detection of copy number variants (CNVs) in the 22q11.2 region. These structural variants were...
PERIPHERAL NERVE BLOCK OF THE FOOT – UTILITY IN DERMATOLOGIC SURGERY
Teixeira, Vera; Cabral, Rita; Vieira, Ricardo; Figueiredo, AméricoIntroduction: Skin cancer of the feet require quick surgical management with the less as possible organic impact, especially in elderly patients with multiple comorbidities. The techniques of regional block anesthesia are relatively easy to perform and safe when performed rigorously. Discussion: The sensitive innervation of the feet depends on five nervous branches: posterior tibial nerve, deep peroneal nerve, ...
METASTATIC CUTANEOUS PLASMOCYTOMA IN A PATIENT LINEAR MORPHEA AND GENITAL LICHE...
Pereira, Neide; Cabral, Rita; Gonçalo, MargaridaBackground: Coexistence of lichen sclerosus and morphea, in most cases with extragenital localization, has been reported in the literature. Case report: A 58-year-old woman presented in 1998 with sclerotic and atrophic linear plaques on the right hemibody, whose histopathological study was compatible with linear morphea. Nine years later, on the residual atrophic areas, small whitish lesions grouped into plaque...