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Arterio-arterial graft – an option for hemodialysis patients with exhaustion of...

Castro, A.; Almeida, P.; Silva, F.; Rego, D.; Tavares, J.; Santos, J.; Silva, F.; Queirós, J.; Cabrita, A.; Almeida, R.

Introduction: Vascular access (VA) for hemodialysis (HD) is the lifeline for End Stage Renal Disease (ESRD) patients. Long-term HD patients often have exhaustion of their venous patrimony for an autologous VA construction and, sometimes, even for a central venous catheter (CVC) placement. Case report: We describe the case of a 43-year-old woman with ESRD due to lupus nephritis, on maintenance HD since 2009. She...


Acute tubulointersticial nephritis with uveitis: A report of two cases

Silva, F.; Correia, S.; Castro, A.; Moreira, C.; Santos, S.; Malheiro, J.; Santos, J.; Martins, L.; Cabrita, A.

Tubulointersticial nephritis and uveitis syndrome is an idiopathic and rare cause of acute kidney injury that should not overlooked, because it usually requires specific therapeutic interventions. We report two distinct cases: a young and an elder female. Both cases presented with unspecific constitutional symptoms but had different onset of renal and ocular involvement. Both were treated with topical and syste...


Biomarkers and Imaging Findings of Anderson-Fabry Disease-What We Know Now

Beirão, I.; Cabrita, A.; Torres, M.; Silva, F.; Aguiar, P.; Laranjeira, F.; Gomes, A.

Anderson-Fabry disease (AFD) is an X-linked lysosomal storage disorder, caused by deficiency or absence of the alpha-galactosidase A activity, with a consequent glycosphingolipid accumulation. Biomarkers and imaging findings may be useful for diagnosis, identification of an organ involvement, therapy monitoring and prognosis. The aim of this article is to review the current available literature on biomarkers an...


Monoclonal gammopathy of renal significance: Diagnostic workup

Correia, S.; Santos, S.; Malheiro, J.; Cabrita, A.; Martins, L.; Santos, J.

The clinical spectrum of diseases associated with monoclonal gammopathies is wide and they are most commonly the consequence of renal deposition of monoclonal immunoglobulin or its components. The differential diagnosis is difficult and renal biopsy is essential. To distinguish many of these pathologies is necessary to use techniques that are not always available, even in tertiary central hospitals. This review...


Are we building too many arteriovenous fistulas? A single-center experience

Leal-Moreira, C.; Teixeira, V.; Bessa, L.; Queirós, J.; Silva, F.; Cabrita, A.

Introduction: Arteriovenous fistula has been associated with improved morbimortality in hemodialysis patients. This has resulted in the “fistula First, catheter last” initiative. Nonetheless, the survival benefit of arteriovenous fistula has been questioned. Methods: We conducted a retrospective observational study of all patients with non-end stage renal disease referred for first vascular access building betw...


Effects of biochar inclusion on in vitro rumen fermentation parameters

Rodrigues, A.; Maia, M.; Cabrita, A.; Oliveira, H.; Bernardo, M.; Fonseca, I.; Trindade, H.; Pereira, José Luís; Fonseca, A.


Formability of a wire arc deposited aluminium alloy

Silva, C. M. A.; Bragança, Ivo; Cabrita, A.; Quintino, L.; Martins, P. A. F.

This paper is focused on the formability of the aluminium alloy AA5083 deposited by wire arc additive manufacturing (WAAM). The presentation draws from metal deposition with a robotic welding system to mechanical and formability characterization by means of standard test specimens. Finite element analysis using porous metal plasticity is utilized to model strain hardening and the changes in porosity due to plas...


BK virus nephropathy in kidney transplantation - A literature review following ...

Barreto, P.; Almeida, M.; Dias, L.; Vieira, P.; Pedroso, S.; Martins, L.; Castro-Henriques, A.; Cabrita, A.

Over the last 15 years, better immunosuppressive drugs have decreased acute rejection rates in kidney transplantation but have also led to an increase in the incidence and impact of BK virus nephropathy. The authors report the case of a 62 -year -old man submitted to a renal transplant of a deceased donor with an immunosuppression regimen free of rabbit anti -thymocyte globulin and tacrolimus, in whom BK nephro...


Implications for patients waiting for a kidney transplant of using the calculat...

Magriço, R.; Malheiro, J.; Tafulo, S.; Pedroso, S.; Almeida, M.; Martins, L.; Dias, L.; Castro-Henriques, A.; Cabrita, A.

Introduction: Kidney transplant improves survival even in highly‑sensitized (HS) patients. To overcome their disadvantage in accessing transplantation, those with high Complement Dependent Cytotoxic PRA (CDC‑PRA) receive additional points during allocation. Whether this strategy reaches all HS patients and how long they wait for a transplant is largely undetermined. Methods: Patients on our unit’s active wait‑l...


Malignancy after renal transplantation: a single-centre experience

Vieira, P.; Bareto, P.; Pedroso, S.; Almeida, M.; Martins, L.; Dias, L.; Castro-Henriques, A.; Cabrita, A.

Introduction: Malignancy management in renal transplant recipients is becoming a major factor affecting long‑term patient survival. Thus, we intended to evaluate both incidence and prognosis of malignant diseases following renal transplantation at a single centre in Portugal. Methods: We studied retrospectively the 2,358 patients who underwent kidney transplantation (KT) between 1983 and 2014. Apart from descri...


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