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Genetic polymorphism of CYP2D6, GSTM1 and NAT2 and susceptibility to haematolog...

Lemos, MC; Cabrita, FJ; Silva, HA; Vivan, M; Plácido, F; Regateiro, FJ

Xenobiotic-metabolizing enzymes constitute an important line of defence against a variety of carcinogens. Many are polymorphic, constituting the basis for the wide inter-individual variation in metabolic capacity and possibly a source of variation in the susceptibility to chemical-induced carcinogenesis. The aim of this study was to determine the existence of any association between the main genetic polymorphis...

Date: 1999   |   Origin: Repositório do Centro Hospitalar e Universitário de Coimbra
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