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Sequential Morphological Changes in the CNV Net after Intravitreal Anti-VEGF Ev...

Marques, JP; Costa, JF; Marques, M; Cachulo, ML; Figueira, J; Silva, R

PURPOSE: To assess and describe sequential morphological changes in the choroidal neovascularization (CNV) net using optical coherence tomography angiography (OCTA) in patients undergoing treatment with intravitreal antivascular endothelial growth factor (VEGF). METHODS: Prospective cohort study. OCTA was performed sequentially: before (t0), 1 h (t1), 1 week (t2) and 1 month after the injection (t3), using Avan...


Treatment of Retinal Vein Occlusion with Ranibizumab in Clinical Practice: Long...

Farinha, C; Marques, JP; Almeida, E; Baltar, A; Santos, AR; Melo, P; Costa, M; Figueira, J; Cachulo, ML; Pires, I; Silva, R

To evaluate long-term results and predictors of efficacy in patients with macular edema due to retinal vein occlusion (RVO) treated with intravitreal ranibizumab in a clinical practice setting.


Progression of myopic maculopathy after treatment of choroidal neovascularization

Farinha, CL; Baltar, AS; Nunes, SG; Figueira, JP; Pires, IA; Cachulo, ML; Silva, RM

Purpose: To evaluate the long-term progression of myopic maculopathy and functional outcome after treatment of myopic choroidal neovascularization (CNV) with photodynamic therapy (PDT) and/or intravitreal ranibizumab (IVR). Methods: Retrospective study with a cross-sectional evaluation. Eyes were assigned to 4 groups (PDT, IVR, PDT + IVR, dry myopic maculopathy) and evaluated with best-corrected visual acuity, ...


Long-term chorioretinal changes after photodynamic therapy for chronic central ...

Vasconcelos, H; Marques, I; Santos, AR; Melo, P; Pires, I; Figueira, J; Faria de Abreu, J; Cachulo, ML; Silva, R

PURPOSE: To evaluate morphological and functional chorioretinal changes 5 years after standard photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC). METHODS: A retrospective, nonrandomized study, including patients with chronic CSC treated with standard PDT and followed for at least 60 months. All patients underwent a complete ophthalmological examination, and the location and number of...


Ocular Risk Factors for Exudative AMD: A Novel Semiautomated Grading System

Marques, JP; Costa, M; Melo, P; Oliveira, CM; Pires, I; Cachulo, ML; Figueira, J; Silva, R

Purpose. To evaluate the contribution of the ocular risk factors in the conversion of the fellow eye of patients with unilateral exudative AMD, using a novel semiautomated grading system. Materials and Methods. Single-center, retrospective study including 89 consecutive patients with unilateral exudative AMD and ≥3 years of followup. Baseline color fundus photographs were graded using an innovative grading soft...


Long-term follow-up of myopic choroidal neovascularization treated with ranibiz...

Franqueira, N; Cachulo, ML; Pires, I; Fonseca, P; Marques, I; Figueira, J; Silva, R

PURPOSE: To evaluate the long-term safety and efficacy of intravitreal ranibizumab in the treatment of myopic choroidal neovascularization (CNV). METHODS: Three-year retrospective, nonrandomized, interventional case series. Forty eyes of 39 patients with myopic CNV were included; 15 with previous photodynamic therapy, and 25 naïve eyes. Best-corrected visual acuity (BCVA) changes, central foveal thickness (CFT)...


Terapêutica Fotodinâmica no tratamento da Coriorretinopatia Serosa Central Crón...

Gregório, T; Pires, I; Cachulo, ML; Figueira, J; Fonseca, P; Santos, AR; Oliveiros, B; Silva, R


Antiangiogénicos na Degenerescência Macular Relacionada com a Idade: a medicina...

Faria de Abreu, JR; Silva, R; Cachulo, ML; Figueira, J; Pires, I; Fonseca, P; Murta, JN


Intravitreal ranibizumab for myopic choroidal neovascularization: 12-month results

Silva, RM; Ruiz-Moreno, JM; Rosa, P; Carneiro, A; Nascimento, J; Rito, LF; Cachulo, ML; Carvalheira, F; Murta, JN

PURPOSE: The purpose of this study was to evaluate the safety and efficacy of intravitreal ranibizumab after 12 months in the treatment of choroidal neovascularization secondary to pathologic myopia. METHODS: This was a prospective, multicenter, consecutive, nonrandomized, interventional case series. The study included 34 eyes of 32 patients with choroidal neovascularization secondary to pathologic myopia; 13 e...


Chorioretinal anastomosis and photodynamic therapy:a two-year follow-up study

Silva, RM; Figueira, J; Cachulo, ML; Duarte, L; Faria de Abreu, JR; Cunha-Vaz, JG

BACKGROUND: To evaluate the two-year efficacy of photodynamic therapy with Visudyne (PDT) in neovascular age-related macular degeneration (AMD) eyes with chorioretinal anastomosis (CRA). METHODS: A non-randomized, institutional, prospective study, of 28 consecutive eyes of 23 patients, with CRA, treated with PDT. Masked best corrected visual acuity (VA) and angiographic features at baseline and during the perio...


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